24. When given an image of a cardiac contractile cell, such as the one belo describe the steps that occur during excitation-contraction coupling (the "before op 1" step show with the squiggly red arrow below), contraction (steps 1-6 below) AND relaxation (steps 7-10 belowl). Be sure to fully describe the role of Ca*2 ATPase and Na Ca+2 exchanger (NCX) in steps 9 and 101 ECF ICF SR Ca2+ RyR 1. Ca sparks Ca signal Contraction Ltype Ca channel 2 K ATP ATP 3 Na 3 Nat Ca Sarcoplasmic reticulum (SR) Cal stores TALL NCX Relaxation Ca2+ oe FI Actin Myosin

24. When given an image of a cardiac contractile cell, such as the one belo describe the steps that occur during excitation-contraction coupling (the "before op 1" step show with the squiggly red arrow below), contraction (steps 1-6 below) AND relaxation (steps 7-10 belowl). Be sure to fully describe the role of Ca*2 ATPase and Na Ca+2 exchanger (NCX) in steps 9 and 101 ECF ICF SR Ca2+ RyR 1. Ca sparks Ca signal Contraction Ltype Ca channel 2 K ATP ATP 3 Na 3 Nat Ca Sarcoplasmic reticulum (SR) Cal stores TALL NCX Relaxation Ca2+ oe FI Actin Myosin

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

See similar textbooks

Related questions

Q: Explain the Mechanism of action of RAAS in response to fall in NaCl

A: The renin-angiotensin-aldosterone system (RAAS), is a hormone system that controls blood pressure,…

Q: 25. Compare the contraction of a single cardiac muscle fiber to a skeletal muscle fiber in terms of…

A: Muscle is one of the tissue types in the body that brings about contraction and relaxation. Muscle…

Q: Bank: A. Contraction C. Relaxation B. Myosin filament D. Actin filament C. Endocrine E. Contact…

A: A group of cells that have similar structure and that function together as a unit are known as the…

Q: INA (NA) Inj (NA) 0.8 -0.8 -1.6 -2.4 0 How does the relationship between INa and IK change as the…

A: The relationship between the sodium current (INa), the potassium current (IK), and the stimulus…

Q: 1. Cardiomyocytes contractile rate increases as Ca2+ levels in cytosol rise. Releasing of Ca²+ to…

A: Cells can respond to environmental signals via signal transduction pathways. A signal is amplified…

Q: Categorize the feedback mechanisms components below during BP regulation. stretch pressure receptor…

A: 1. Sensor 2 effector

Q: If you were a medical researcher, what other areas of the blood-clotting pathway would you target…

A: A stroke may be a medical emergency during which the blood supply to any portion of the brain is…

Q: Heurotransmitters and their respective receptors influence the propagation of action potentials. Why…

A: Hormones are defined as the type of chemical messengers that are directly released into the…

Q: Consider the mechanism of net NaCl secretion across an epithelium shown below: b) What is the…

A: Introduction: Sodium potassium pump is a type of coupled or co-transport in which transport of one…

Q: 08.

A: Muscle is a specialized tissue derived from mesodermal origin. It contributes about 50percent of the…

Q: Descrive (in the correct order) the sequence of the blood flow through a four chambered mammalian…

A: The function of the heart is to pump oxygenated blood to various body organs. It also pumps…

Q: | Pra'i t Pk- (transient) | Pca, L; I P- (both transient and leaky) k*out fast +30 Ca2+ in slow…

A: DISCLAIMER : Since you have asked multiple question, we will solve the first question for you. If…

Q: This question relates to the "Tength constant" (A) and decay of a local graded potential over…

A: It is assumed that the membrane potential is identical in different parts of the membrane in a…

Q: The length of the cardiac action potential, at 200-300 msec, is dependent upon the: plateau phase. O…

A: Action potential Sudden rise and fall in membrane voltage in a characteristic pattern.…

Q: Explain how does Ohm’s law relates to our Core Concept of flow down gradients in physiology

A: According to ohm's law, the amount of current flow or potential difference between two points is…

Q: Using this diagram and the points indicated (A, B, C) please explain how to treat congestive heart…

A: A chronic progressive condition affecting the cardiac muscle's pumping power is Congestive heart…

Q: Vascular endothelial growth factor receptor 2 (VEGFR-2) is an endothelial cell-specific receptor…

A: Angiogenesis, the formation of new blood vessels from pre-existing ones, plays a critical role in…

Q: The diagram below depicts the proportion of oxygen bound (e) by haemoglobin at different partial…

A: Hemoglobin is a pigmented molecule present in blood that delivers oxygen to tissues from the lungs.…

Q: Cardiac myocytes, which of these downstream activities WOULD NOT occur when norepinephrine binds to…

A: Cardiac myocyte is the functional unit of the organ. The cell is delimited by a lipid membrane,…

Q: 4. Illustrate (draw) what an action potential might look like with the following voltage-gated…

A: In this investigation, we look at how a few voltage-gated channels influence the appearance and…

Q: Which of these curves shows Hb with no BPG bound?

A: The correct answer is "d"

Q: After repolarization, the sodium ions are found neuron. This reversal of ions can be fixed by the…

A: Following an action potential and the subsequent repolarization phase, there is a temporary reversal…

Q: Reducing the saline [Cl-] from 550 mM to 350 mM resulted in a change in the reversal potential of a…

A: The processing of nervous signals through neurotransmitters is regulated by neurons.…

Q: How many iters of half normal saline IV soktion with a concentration of 0.45% (m/v) can be prepared…

A: Dilution is the process of decreasing the concentration of solute in a solution generally by mixing…

Q: functional barrier that prevents passage of antibiotics, and toxins from the blood to nervous 10.…

A: The nervous system controls and coordinates all the activities of the human body. It is classified…

Q: (1)B (2C D(3) (0)A E (4) The figure above represents action potential in plateau for cardiac muscle…

A: The cardiac action potential is a change in the membrane potential of the heart cells. The movement…

Q: What happens to membrane potential during manipulation 4 in the attached figure (Figure 4.13 of the…

A: The objective of the question is to understand the effect of metabolic inhibitors, such as…

Q: Ventral tegmental area (VTA) neurons in the brain have been implicated in the etiology of symptoms…

A: The VTA or the ventral tegmental area neurons are the group of neurons present in the midline on the…

Q: A bat is 100 ft. below and to the right of a moth, as shown in the diagram below. At this distance,…

A: A bat uses sonar to navigate and hunt in the dark. It does this by emitting high-frequency sound…

Q: Briefly describe one voltage-gated ion channel and two protein pumps found in the heart. In your…

A: Introduction Voltage-gated Ion channels are a type of transmembrane protein that forms Ion channels…

Q: Na, K and Cl behavior during depolarization, repolarization and hyperpolarization transient changes…

A: Electrically excitable cells are activated by electrical signals from the nervous system. Electrical…

Q: +20- +10 1 Pk; IPca, L Self-induced È of action potential - 10 -20 -30- Pca", L; i Pca,T Threshold…

A: The heart is responsible foe pumping of blood in the body. The blood is pumped due to rhythmic…

Q: Match the phases of action potential +20 -40 -60 0.8 1.6 a [Choose ] [ Choose] c and d V [Choose )…

A: The heart muscles have the capability of producing electrical impulses and by using this electrical…

Q: 6) A male patient has been given a loading dose of digoxin of 1000 micrograms in divided doses by…

A: Maintenance rate of a drug to be administered that is equal to its steady state plasma concentration…

Q: Identify the differences between type A and type B intercalated cells; under which condition is…

A: Nephrons are the functional units of the kidneys. A nephron consists of tubules and associated…

Q: Ad-dimer will be elevated during: (select all that apply) ischemic stroke hemorrhagic stroke O…

A: d- dimer is a protein fragment, it is produced when the blood clot get dissolves in the body. The…

Q: A drug that blocks the cardiac muscarinic receptor might be expected to: Increased heart rate…

A: Cardiac muscarinic antagonists are the agent that inhibits the function of the muscarinic receptors.…

Q: Below are two action potentials (recording 1 (normal) vs. recording 2 (condition)) measured in the…

Q: 195. Correctly match Column-I with Column-II :- Column-I Column-II Cardiac A arrest Heart not…

A: Introduction: The heart is a muscular organ in most animals, which pumps blood through the blood…

Q: Q4/ Answer with either (True) or (False) for the following: 1- Simple diffusion is the net movement…

Q: Calcium channel-blocking drugs are sometimes given to patients with heart problems. If a patient is…

A: We know that Calcium channel blockers are a group of antihypertensive drugs, which disrupt the…

Q: A loss-of-function mutation in the ion channel responsible for the generation of end-plate…

A: Please follow step 2 for detailed expalanation.

Q: d) Use the graph below to complete the table: +40 0 What channel is open? What channel is closed? A…

A: Neurotransmitters can serve as chemical messengers for ion channels, neurotransmitter mainly causes…

Question

24. When given an image of a cardiac contractile cell, such as the one belo describe
the steps that occur during excitation-contraction coupling (the "before op 1" step
show with the squiggly red arrow below), contraction (steps 1-6 below) AND
relaxation (steps 7-10 belowl). Be sure to fully describe the role of Ca*2 ATPase and
Na Ca+2 exchanger (NCX) in steps 9 and 101
ECF
ICF
SR
Ca2+
RyR
1.
Ca sparks
Ca signal
Contraction
Ltype
Ca
channel
2 K
ATP
ATP
3 Na
3 Nat Ca
Sarcoplasmic reticulum
(SR)
Cal stores
TALL
NCX
Relaxation
Ca2+
oe
FI
Actin
Myosin

Expert Solution

Step 1

The muscle contraction in the cardiac muscles depends on actin and myosin introduction. Calcium ions are very much important in this interactions. The given image represent the molecular events of muscle contraction in cardiac muscles.