Analysis 7 Days 14 Days no. of events/total no. Risk Difference (95% CI) percentage points -1.6 (-4.0 to 0.8) Intention-to-treat Per-protocol 261/1802 286/1779 178/1370 222/1483 -2.0 (-4.5 to 0.6) Modified intention-to-treat 247/1788 272/1765 -1.6 (-3.9 to 0.7) -8.0-6.0-4.0 -2.0 0.0 2.0 4.0 6.0 8.0 7 Days Noninferior 7 Days Inferior
Analysis 7 Days 14 Days no. of events/total no. Risk Difference (95% CI) percentage points -1.6 (-4.0 to 0.8) Intention-to-treat Per-protocol 261/1802 286/1779 178/1370 222/1483 -2.0 (-4.5 to 0.6) Modified intention-to-treat 247/1788 272/1765 -1.6 (-3.9 to 0.7) -8.0-6.0-4.0 -2.0 0.0 2.0 4.0 6.0 8.0 7 Days Noninferior 7 Days Inferior
Glencoe Algebra 1, Student Edition, 9780079039897, 0079039898, 2018
18th Edition
ISBN:9780079039897
Author:Carter
Publisher:Carter
Chapter10: Statistics
Section10.1: Measures Of Center
Problem 4GP
Related questions
Question
Can you help me understand this analysis?
A 95.7% confidence interval is shown for the intention-to-treat analysis (accounting for alpha spending in interim analyses), and 95% confidence intervals are shown for the other two analyses. The widths of the confidence intervals have not been adjusted for multiplicity. The dashed line indicates the noninferiority margin of 4 percentage points.

Transcribed Image Text:Analysis
7 Days
14 Days
no. of events/total no.
Risk Difference (95% CI)
percentage points
-1.6 (-4.0 to 0.8)
Intention-to-treat
Per-protocol
261/1802 286/1779
178/1370 222/1483
-2.0 (-4.5 to 0.6)
Modified intention-to-treat
247/1788
272/1765
-1.6 (-3.9 to 0.7)
-8.0-6.0-4.0 -2.0 0.0
2.0 4.0 6.0
8.0
7 Days Noninferior
7 Days Inferior
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