An investigator hypothesizes that the improvement rate associated with a placebo is P1 = 0.45, and that the improvement rate associated with an active drug is P2 = 0.65. The plan is to perform a two-tailed test. Use SAS to complete each problem below. please present results with numbers and the code to make sure it works.
An investigator hypothesizes that the improvement rate associated with a placebo is P1 = 0.45, and that the improvement rate associated with an active drug is P2 = 0.65. The plan is to perform a two-tailed test. Use SAS to complete each problem below.
please present results with numbers and the code to make sure it works.
(b)How large must the
(d)Suppose that instead of accruing an equal number of patients on each treatment arm, you allocate 1.5 patients to the new treatment for every patient on standard treatment. What sample size is required on each arm to guarantee 85% power with a level 0.05?How does the sample size computed here compare with the total required sample size in (b)?
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