An analgesic drug was given to an elderly patient (70 kg body weight) by IV bolus injection at a dose of 800 mg. The drug has apparent volume of distribution of 21 L, and elimination half-life of 6 hours. Calculate the metabolism rate constant (Km) if you know that 80 % of the drug is metabolized in the liver and 20 % is excreted unchanged in urine

An analgesic drug was given to an elderly patient (70 kg body weight) by IV bolus injection at a dose of 800 mg. The drug has apparent volume of distribution of 21 L, and elimination half-life of 6 hours. Calculate the metabolism rate constant (Km) if you know that 80 % of the drug is metabolized in the liver and 20 % is excreted unchanged in urine

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter9: Parenteral Medication Labels And Dosage Calculation

Section: Chapter Questions

Problem 7.9P

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