Alkaptonuria is a metabolic disorder in which affected people produce black urine. Alkaptonuria results from an allele (a) that is recessive to the allele for normal metabolism (A). Sally has normal metabolism, buther brother has alkaptonuria. Sally’s father has alkaptonuria, and her mother has normal metabolism. Q. If Sally marries a man with alkaptonuria, what is the probability that their first child will have alkaptonuria?

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