After taking Anemovax vaccine, it is recommended that the booster dose be Dendrovax. The combination of the two vaccines lead to a faster formation of COVID-19 antibodies under acidic pH. Therefore, the kinetics of the formation of COVID-19 antibodies by the Dendrovax and Anemovax vaccine under different acidic media was analyzed via methods of initial rates at 35°C. The results of the experiment are shown in the table below. Table 3. Kinetic data for the reaction above Run Temp, °C [Dendrovax], M [Anemovax], M 1 29.0 0.150 0.200 2 3 4 5 6 7 29.0 29.0 29.0 29.0 15.0 40.0 0.450 0.450 0.450 0.450 0.600 0.450 0.200 0.100 0.200 0.200 0.200 0.300 pH 2.00 2.00 2.50 2.50 3.00 2.00 2.50 Rate, M/s 4.500 x 10-3 1.350 x 10-4 6.750 x 10-6 1.350 x 10-5 1.350 x 10-6 1.800 x 10-4 2.025 x 10-5 a. Determine the rate order with respect to each reactant. Note: Use linear regression with at least 3 data points, and pH = -log[H+] b. What is the overall rate order of the reaction? c. What is the rate constant of Run 6, including correct units? d. Run 6 was also conducted using a different temperature. If the value of the rate constant is 7.43x10² units at 40ºC, what is the activation energy (kJ/mol) of the reaction?
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
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