Classify each phrase as describing a competitive inhibitor, uncompetitive inhibitor, or mixed (mixed noncompetitive) inhibitor. Note that Km refers to apparent Km. Competitive inhibitor structurally similar to substrate when present, Km of enzyme will decrease prevents substrate from binding enzyme Uncompetitive inhibitor when present, Vmax of enzyme is unaffected binds enzyme-substrate complex only Mixed inhibitor binds either enzyme or enzyme- substrate complex when present, Km of enzyme will either increase or decrease
Classify each phrase as describing a competitive inhibitor, uncompetitive inhibitor, or mixed (mixed noncompetitive) inhibitor. Note that Km refers to apparent Km. Competitive inhibitor structurally similar to substrate when present, Km of enzyme will decrease prevents substrate from binding enzyme Uncompetitive inhibitor when present, Vmax of enzyme is unaffected binds enzyme-substrate complex only Mixed inhibitor binds either enzyme or enzyme- substrate complex when present, Km of enzyme will either increase or decrease
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:Classify each phrase as describing a competitive inhibitor, uncompetitive inhibitor, or mixed (mixed noncompetitive) inhibitor.
Note that Km refers to apparent Km ·
Competitive inhibitor
structurally similar to substrate
when present, Km of enzyme will decrease
prevents substrate from binding enzyme
Uncompetitive inhibitor
when present, Vmax of enzyme is unaffected
binds enzyme-substrate complex only
Answer Bank
Mixed inhibitor
binds either enzyme or enzyme-
substrate complex
when present, Km of enzyme will either
increase or decrease
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