13. An enzyme is shown below, along with its substrate. Label the enzyme, the enzyme active site, and the substrate. 14. Now add three amino acid side chains from your amino acid reference sheet that might exist in the enzyme active site. Choose side chains that will interact with the substrate shown and draw and label the interactions that you would expect to see between the side chains you draw and the substrate shown. For the interactions with each side chain, show one or two of the strongest possible interactions with the substrate.

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Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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20 Common Amino Acids (neutral form)
Methionine
(Met, M)
Phenylalanine
(Phe, F)
NONPOLAR AMINO ACIDS
Leucine
Isoleucine
(Leu, L)
(Ile, I)
Valine
(Val, V)
H,N-CH-C-OH
H;N-CH-C-OH
Alanine
CH;
HN-CH-C
CH-CH,
Glycine
(Gly, G)
CH-C-
OH
(Ala, A)
H2N-
OH
CH2
CH;
HN-CH-C-OH
CH
CH-CH,
CH-CH,
CH
HN-CH-C-OH H,N-CH-C-OH
CH
CH
CH,
CH,
H.
CH
Tyrosine
(Tyr, Y)
POLAR NEUTRAL AMINO ACIDS
Tryptophan
(Trp, W) O
HN-CH-C-OH
Glutamine
Proline
Asрaragine
(Asn, N)
H,N-CH-C-OH
(Gln, Q)
Threonine
(Pro, P)
Serine
(Ser, S)
(The, T)
H,N-CH-C-OH
CH
CH,
C-OH
H,N-CH-C-
OH
CH
CH,
H,N-CH-C-OH
CH2
H,N
CH-
-он
HN
HN
CH-OH
CH
NH,
NH,
OH
CH,
CYSTEINE
POLAR ACIDIC AMINO ACIDS
POLAR BASIC AMINO ACIDS
Cysteine
Arginine
(Arg, R)
(Cys, C)
Glutamie
Acid
Lysine
(Lys, K)
HN-CH-C-OH
Aspartic
Acid
Histidine
(His, H)
(Glu, E)
(Asp, D)
H,N-CH-C-OH
CH,
H,N-CH-C-OH
HN-CH-C
OH
CH,
CH
CH2
H,N-CH-C
H,N-CH-C-
OH
CH
SH
CH,
CH
NH
"recall that Cya har the unique
ability to form diulfide bonds
and participate in oxidation-
reduction reactions
CNH
CH,
OH
NH,
NH2
NH
Transcribed Image Text:20 Common Amino Acids (neutral form) Methionine (Met, M) Phenylalanine (Phe, F) NONPOLAR AMINO ACIDS Leucine Isoleucine (Leu, L) (Ile, I) Valine (Val, V) H,N-CH-C-OH H;N-CH-C-OH Alanine CH; HN-CH-C CH-CH, Glycine (Gly, G) CH-C- OH (Ala, A) H2N- OH CH2 CH; HN-CH-C-OH CH CH-CH, CH-CH, CH HN-CH-C-OH H,N-CH-C-OH CH CH CH, CH, H. CH Tyrosine (Tyr, Y) POLAR NEUTRAL AMINO ACIDS Tryptophan (Trp, W) O HN-CH-C-OH Glutamine Proline Asрaragine (Asn, N) H,N-CH-C-OH (Gln, Q) Threonine (Pro, P) Serine (Ser, S) (The, T) H,N-CH-C-OH CH CH, C-OH H,N-CH-C- OH CH CH, H,N-CH-C-OH CH2 H,N CH- -он HN HN CH-OH CH NH, NH, OH CH, CYSTEINE POLAR ACIDIC AMINO ACIDS POLAR BASIC AMINO ACIDS Cysteine Arginine (Arg, R) (Cys, C) Glutamie Acid Lysine (Lys, K) HN-CH-C-OH Aspartic Acid Histidine (His, H) (Glu, E) (Asp, D) H,N-CH-C-OH CH, H,N-CH-C-OH HN-CH-C OH CH, CH CH2 H,N-CH-C H,N-CH-C- OH CH SH CH, CH NH "recall that Cya har the unique ability to form diulfide bonds and participate in oxidation- reduction reactions CNH CH, OH NH, NH2 NH
13. An enzyme is shown below, along with its substrate. Label the enzyme, the enzyme active
site, and the substrate.
14. Now add three amino acid side chains from your amino acid reference sheet that might exist
in the enzyme active site. Choose side chains that will interact with the substrate shown and
draw and label the interactions that you would expect to see between the side chains you
draw and the substrate shown. For the interactions with each side chain, show one or two of
the strongest possible interactions with the substrate.
Transcribed Image Text:13. An enzyme is shown below, along with its substrate. Label the enzyme, the enzyme active site, and the substrate. 14. Now add three amino acid side chains from your amino acid reference sheet that might exist in the enzyme active site. Choose side chains that will interact with the substrate shown and draw and label the interactions that you would expect to see between the side chains you draw and the substrate shown. For the interactions with each side chain, show one or two of the strongest possible interactions with the substrate.
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