13. An enzyme is shown below, along with its substrate. Label the enzyme, the enzyme active site, and the substrate. 14. Now add three amino acid side chains from your amino acid reference sheet that might exist in the enzyme active site. Choose side chains that will interact with the substrate shown and draw and label the interactions that you would expect to see between the side chains you draw and the substrate shown. For the interactions with each side chain, show one or two of the strongest possible interactions with the substrate.
13. An enzyme is shown below, along with its substrate. Label the enzyme, the enzyme active site, and the substrate. 14. Now add three amino acid side chains from your amino acid reference sheet that might exist in the enzyme active site. Choose side chains that will interact with the substrate shown and draw and label the interactions that you would expect to see between the side chains you draw and the substrate shown. For the interactions with each side chain, show one or two of the strongest possible interactions with the substrate.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:20 Common Amino Acids (neutral form)
Methionine
(Met, M)
Phenylalanine
(Phe, F)
NONPOLAR AMINO ACIDS
Leucine
Isoleucine
(Leu, L)
(Ile, I)
Valine
(Val, V)
H,N-CH-C-OH
H;N-CH-C-OH
Alanine
CH;
HN-CH-C
CH-CH,
Glycine
(Gly, G)
CH-C-
OH
(Ala, A)
H2N-
OH
CH2
CH;
HN-CH-C-OH
CH
CH-CH,
CH-CH,
CH
HN-CH-C-OH H,N-CH-C-OH
CH
CH
CH,
CH,
H.
CH
Tyrosine
(Tyr, Y)
POLAR NEUTRAL AMINO ACIDS
Tryptophan
(Trp, W) O
HN-CH-C-OH
Glutamine
Proline
Asрaragine
(Asn, N)
H,N-CH-C-OH
(Gln, Q)
Threonine
(Pro, P)
Serine
(Ser, S)
(The, T)
H,N-CH-C-OH
CH
CH,
C-OH
H,N-CH-C-
OH
CH
CH,
H,N-CH-C-OH
CH2
H,N
CH-
-он
HN
HN
CH-OH
CH
NH,
NH,
OH
CH,
CYSTEINE
POLAR ACIDIC AMINO ACIDS
POLAR BASIC AMINO ACIDS
Cysteine
Arginine
(Arg, R)
(Cys, C)
Glutamie
Acid
Lysine
(Lys, K)
HN-CH-C-OH
Aspartic
Acid
Histidine
(His, H)
(Glu, E)
(Asp, D)
H,N-CH-C-OH
CH,
H,N-CH-C-OH
HN-CH-C
OH
CH,
CH
CH2
H,N-CH-C
H,N-CH-C-
OH
CH
SH
CH,
CH
NH
"recall that Cya har the unique
ability to form diulfide bonds
and participate in oxidation-
reduction reactions
CNH
CH,
OH
NH,
NH2
NH

Transcribed Image Text:13. An enzyme is shown below, along with its substrate. Label the enzyme, the enzyme active
site, and the substrate.
14. Now add three amino acid side chains from your amino acid reference sheet that might exist
in the enzyme active site. Choose side chains that will interact with the substrate shown and
draw and label the interactions that you would expect to see between the side chains you
draw and the substrate shown. For the interactions with each side chain, show one or two of
the strongest possible interactions with the substrate.
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