Homework Help is Here – Start Your Trial Now!
Science
Chemistry
Determine whether each of the inhibitors (or inhibitor characteristics) are involved in reversible inhibition or irreversible inhibition. a) inhibitor structure often resembles the substrate structure reversible inhibition b) inhibitor forms a new and permanent covalent bond to the enzyme's active site irreversible inhibition c) sulfanilamide reversible inhibition d) aspirin irreversible inhibition e) inhibitor binds weakly and noncovalently to an enzyme's active site and decreases its activity reversible inhibition f) penicillin V irreversible inhibition g) inhibitor binds weakly and noncovalently to the enzyme at a region other than the active site reversible inhibition h) inhibitors repeatedly attach to and detach from enzyme reversible inhibition i) inhibitor is used in a pathway that is regulated by feedback inhibition reversible inhibition EXPLANATION: Irreversible inhibition occurs when an inhibitor reacts with an enzyme, forming a new and permanent covalent bond to the enzyme. In almost all cases of irreversible inhibition, the new bond is made to the enzyme's active site, which results in complete and permanent loss of the enzyme's activity. Reversible inhibition occurs when an inhibitor is weakly bound to an enzyme and decreases its activity. Like the substrates, reversible inhibitors are specific for particular enzymes. Reversible inhibitors do not form covalent bonds to the enzyme, therefore they repeatedly attach to and detach from enzymes.

Determine whether each of the inhibitors (or inhibitor characteristics) are involved in reversible inhibition or irreversible inhibition. a) inhibitor structure often resembles the substrate structure reversible inhibition b) inhibitor forms a new and permanent covalent bond to the enzyme's active site irreversible inhibition c) sulfanilamide reversible inhibition d) aspirin irreversible inhibition e) inhibitor binds weakly and noncovalently to an enzyme's active site and decreases its activity reversible inhibition f) penicillin V irreversible inhibition g) inhibitor binds weakly and noncovalently to the enzyme at a region other than the active site reversible inhibition h) inhibitors repeatedly attach to and detach from enzyme reversible inhibition i) inhibitor is used in a pathway that is regulated by feedback inhibition reversible inhibition EXPLANATION: Irreversible inhibition occurs when an inhibitor reacts with an enzyme, forming a new and permanent covalent bond to the enzyme. In almost all cases of irreversible inhibition, the new bond is made to the enzyme's active site, which results in complete and permanent loss of the enzyme's activity. Reversible inhibition occurs when an inhibitor is weakly bound to an enzyme and decreases its activity. Like the substrates, reversible inhibitors are specific for particular enzymes. Reversible inhibitors do not form covalent bonds to the enzyme, therefore they repeatedly attach to and detach from enzymes.

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
See similar textbooks
icon
Related questions
Question

I don't get it at all my homework. I struggled with this question. Can you help me? Can you explain to me?

Determine whether each of the inhibitors (or inhibitor characteristics) are involved in reversible inhibition or irreversible inhibition. a) inhibitor structure often resembles the substrate structure reversible inhibition b) inhibitor forms a new and permanent covalent bond to the enzyme's active site irreversible inhibition c) sulfanilamide reversible inhibition d) aspirin irreversible inhibition e) inhibitor binds weakly and noncovalently to an enzyme's active site and decreases its activity reversible inhibition f) penicillin V irreversible inhibition g) inhibitor binds weakly and noncovalently to the enzyme at a region other than the active site reversible inhibition h) inhibitors repeatedly attach to and detach from enzyme reversible inhibition i) inhibitor is used in a pathway that is regulated by feedback inhibition reversible inhibition EXPLANATION: Irreversible inhibition occurs when an inhibitor reacts with an enzyme, forming a new and permanent covalent bond to the enzyme. In almost all cases of irreversible inhibition, the new bond is made to the enzyme's active site, which results in complete and permanent loss of the enzyme's activity. Reversible inhibition occurs when an inhibitor is weakly bound to an enzyme and decreases its activity. Like the substrates, reversible inhibitors are specific for particular enzymes. Reversible inhibitors do not form covalent bonds to the enzyme, therefore they repeatedly attach to and detach from enzymes.
Transcribed Image Text:Determine whether each of the inhibitors (or inhibitor characteristics) are involved in reversible inhibition or irreversible inhibition. a) inhibitor structure often resembles the substrate structure reversible inhibition b) inhibitor forms a new and permanent covalent bond to the enzyme's active site irreversible inhibition c) sulfanilamide reversible inhibition d) aspirin irreversible inhibition e) inhibitor binds weakly and noncovalently to an enzyme's active site and decreases its activity reversible inhibition f) penicillin V irreversible inhibition g) inhibitor binds weakly and noncovalently to the enzyme at a region other than the active site reversible inhibition h) inhibitors repeatedly attach to and detach from enzyme reversible inhibition i) inhibitor is used in a pathway that is regulated by feedback inhibition reversible inhibition EXPLANATION: Irreversible inhibition occurs when an inhibitor reacts with an enzyme, forming a new and permanent covalent bond to the enzyme. In almost all cases of irreversible inhibition, the new bond is made to the enzyme's active site, which results in complete and permanent loss of the enzyme's activity. Reversible inhibition occurs when an inhibitor is weakly bound to an enzyme and decreases its activity. Like the substrates, reversible inhibitors are specific for particular enzymes. Reversible inhibitors do not form covalent bonds to the enzyme, therefore they repeatedly attach to and detach from enzymes.
Expert Solution
steps

Step by step

Solved in 4 steps with 3 images

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Vitamins and Coenzymes
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY
SEE MORE TEXTBOOKS