Propose an efficient synthesis for the given transformation. o This transformation can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A t-BuOK F 1) HC=CNa; 2) H3O+ K + En MeONa B 1); 2) H3O+ G NaH L DMP or PCC C 1); 2) H3O+ H MCPBA (RCO 3H) M MeOH, H₂SO4 D Mg 1 Br2, hv N H₂SO4, H₂O, HgSO4 E H₂, Lindlar's cat. J HBr (xs), heat 1) R₂BH; 2) H₂O2, NaOH
Propose an efficient synthesis for the given transformation. o This transformation can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A t-BuOK F 1) HC=CNa; 2) H3O+ K + En MeONa B 1); 2) H3O+ G NaH L DMP or PCC C 1); 2) H3O+ H MCPBA (RCO 3H) M MeOH, H₂SO4 D Mg 1 Br2, hv N H₂SO4, H₂O, HgSO4 E H₂, Lindlar's cat. J HBr (xs), heat 1) R₂BH; 2) H₂O2, NaOH
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Question
Propose a strategy for the given synthesis.
![Propose an efficient synthesis for the given transformation.
A
This transformation can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in
the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution,
provide just one answer.
t-BuOK
F
1) HC=CNa; 2)
H3O+
K
+
MeONa
En
B
1); 2)
H3O+
G
NaH
L
DMP or PCC
C
1); 2) H3O+
H
MCPBA
(RCO 3H)
M
MeOH, H₂SO4
D
Mg
I
Br2, hv
N
H₂SO4, H₂O,
HgSO4
E
H₂, Lindlar's cat.
HBr (xs), heat
O
1) R₂BH; 2) H₂O2,
NaOH](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd75a0cba-20f2-443d-a1e9-f3f1ac2380ac%2F03904829-2864-450f-a20d-2dc0ff910a17%2F1d8am1s_processed.png&w=3840&q=75)
Transcribed Image Text:Propose an efficient synthesis for the given transformation.
A
This transformation can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in
the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution,
provide just one answer.
t-BuOK
F
1) HC=CNa; 2)
H3O+
K
+
MeONa
En
B
1); 2)
H3O+
G
NaH
L
DMP or PCC
C
1); 2) H3O+
H
MCPBA
(RCO 3H)
M
MeOH, H₂SO4
D
Mg
I
Br2, hv
N
H₂SO4, H₂O,
HgSO4
E
H₂, Lindlar's cat.
HBr (xs), heat
O
1) R₂BH; 2) H₂O2,
NaOH
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