After 10.0 mL of an aqueous solution containing 1.235 mg of a drug extracted with 5.0 mL of toluene the aqueous layer was found to contain 0.346 mg of the compound. (a) Calculate the distribution coefficient for the drug between the two solvents. (b) How many 10.0-mL extractions would be required to recover 99.0% of the drug from 20.0 mL of water? What volume of toluene would be used?

After 10.0 mL of an aqueous solution containing 1.235 mg of a drug extracted with 5.0 mL of toluene the aqueous layer was found to contain 0.346 mg of the compound. (a) Calculate the distribution coefficient for the drug between the two solvents. (b) How many 10.0-mL extractions would be required to recover 99.0% of the drug from 20.0 mL of water? What volume of toluene would be used?

Fundamentals Of Analytical Chemistry

9th Edition

ISBN:9781285640686

Author:Skoog

Publisher:Skoog

Chapter16: Applications Of Neutralization Titrations

Section: Chapter Questions

Problem 16.7QAP

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