Affected female Affected male O Unaffected female Unaffected male IV III 9999 00000 50000 353 180 90/20 160/20 20 160 180/20 20 180/40 20 180/20 250/20 200 20/20160/20 20 200 40/20 20 80 80/40 A) Between 20 and 40 and between 80 and 180, respectively B) Between 20 and 40 and between 160 and 180, respectively C) Between 40 to 80 and between 160 and 180, respectively D) Between 40 to 80 and between 180 and 200, respectively O 40/20 80/20 20 20/20 20 118. A 25-year-old nulligravid woman (individual IV-1 in the pedigree shown) and her 28-year-old husband come to the office for counseling prior to conception. Previous reproductive endocrinologic evaluation of the husband showed no abnormalities. The woman has a family history of fragile X syndrome. The genotype of the CGG trinucleotide repeat length in the 5'-untranslated exon of the FMR1 gene for each individual in the family is indicated. Based on these findings, the repeat length boundaries between normal and premutation and between premutation and full mutation is closest to which of the following?
Affected female Affected male O Unaffected female Unaffected male IV III 9999 00000 50000 353 180 90/20 160/20 20 160 180/20 20 180/40 20 180/20 250/20 200 20/20160/20 20 200 40/20 20 80 80/40 A) Between 20 and 40 and between 80 and 180, respectively B) Between 20 and 40 and between 160 and 180, respectively C) Between 40 to 80 and between 160 and 180, respectively D) Between 40 to 80 and between 180 and 200, respectively O 40/20 80/20 20 20/20 20 118. A 25-year-old nulligravid woman (individual IV-1 in the pedigree shown) and her 28-year-old husband come to the office for counseling prior to conception. Previous reproductive endocrinologic evaluation of the husband showed no abnormalities. The woman has a family history of fragile X syndrome. The genotype of the CGG trinucleotide repeat length in the 5'-untranslated exon of the FMR1 gene for each individual in the family is indicated. Based on these findings, the repeat length boundaries between normal and premutation and between premutation and full mutation is closest to which of the following?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Affected female
Affected male
O Unaffected female
Unaffected male
11
IV
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O
40/20
20
80/40
80
OOT
180 90/20 160/20 20
A) Between 20 and 40 and between 80 and 180, respectively
B) Between 20 and 40 and between 160 and 180, respectively
C) Between 40 to 80 and between 160 and 180, respectively
D) Between 40 to 80 and between 180 and 200, respectively
O
40/20
80/20
160
Wint
Matty Mariant
20
180/20 20
180/40 20 180/20 250/20 200 20/20 160/20 20 200
20
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20/20 20
simp
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118. A 25-year-old nulligravid woman (individual IV-1 in the pedigree shown) and her 28-year-old husband come to the office for counseling prior to conception. Previous
reproductive endocrinologic evaluation of the husband showed no abnormalities. The woman has a family history of fragile X syndrome. The genotype of the CGG
trinucleotide repeat length in the 5'-untranslated exon of the FMR1 gene for each individual in the family is indicated. Based on these findings, the repeat length
boundaries between normal and premutation and between premutation and full mutation is closest to which of the following?
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