Active subunit - A Binding subunit-B) Binding site 1 B subunit binds to a specific molecule on the host cell. 2 Toxin is taken up by endocytosis. 3 Toxin subunits separate allowing the A subunit to enter the cytoplasm, where it exerts its toxic effects. FIGURE 16.11 The Action of an A-B Toxin The structure and mechanisms of uptake of different A-B toxins may vary slightly.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Would an antibody response against the B subunit protect against the effects of the toxin?

Active subunit -
A
Binding subunit-B)
Binding site
1 B subunit binds to a
specific molecule
on the host cell.
2 Toxin is taken up
by endocytosis.
3 Toxin subunits separate allowing
the A subunit to enter the cytoplasm,
where it exerts its toxic effects.
FIGURE 16.11 The Action of an A-B Toxin The structure and
mechanisms of uptake of different A-B toxins may vary slightly.
Transcribed Image Text:Active subunit - A Binding subunit-B) Binding site 1 B subunit binds to a specific molecule on the host cell. 2 Toxin is taken up by endocytosis. 3 Toxin subunits separate allowing the A subunit to enter the cytoplasm, where it exerts its toxic effects. FIGURE 16.11 The Action of an A-B Toxin The structure and mechanisms of uptake of different A-B toxins may vary slightly.
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