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Activation of the insulin receptor initiates an intracellular signaling cascade that leads to the phosphorylation of GLUT4, which causes GLUT4 to adopt an open conformation that allows glucose to diffuse down its concentration gradient into the cell.  True  False 2. Following a high-carbohydrate meal, the majority (~80%) of insulin-stimulated glucose uptake occurs in skeletal muscle.  True  False 3.  Both the GLUT2 and GLUT4 transporters have 12 transmembrane domains.  True  False

Activation of the insulin receptor initiates an intracellular signaling cascade that leads to the phosphorylation of GLUT4, which causes GLUT4 to adopt an open conformation that allows glucose to diffuse down its concentration gradient into the cell.  True  False 2. Following a high-carbohydrate meal, the majority (~80%) of insulin-stimulated glucose uptake occurs in skeletal muscle.  True  False 3.  Both the GLUT2 and GLUT4 transporters have 12 transmembrane domains.  True  False

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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  1. Activation of the insulin receptor initiates an intracellular signaling cascade that leads to the phosphorylation of GLUT4, which causes GLUT4 to adopt an open conformation that allows glucose to diffuse down its concentration gradient into the cell.

     True

     False

    1. 2. Following a high-carbohydrate meal, the majority (~80%) of insulin-stimulated glucose uptake occurs in skeletal muscle.

       True

       False

      3. 

      1. Both the GLUT2 and GLUT4 transporters have 12 transmembrane domains.

         True

         False

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