a)A secondary measure ("response to treatment") was defined as resolution of all symptoms or an improvement in symptoms and ≥ 50% reduction in AHI. In the MAS group 12 patients experienced a "response to treatment". The standard error for the proportion of patients in the MAS group that experience a "response to treatment" is 0.0413 0.1033 0.1633 0.4575 b) Constructing a 95% confidence interval by hand for the population proportion of patients in the MAS group that would experience a "response to treatment", the margin of error is
A study was conducted to compare the efficacy of a mandibular advancement splint (MAS) and a tongue stabilizing device (TSD) in the treatment of obstructive sleep apnea (OSA). Thirty patients (20 male, 10 female) were recruited to the study with fifteen patients being randomly allocated to each treatment group. The efficacy of the treatments were compared using the apnea-hypopnea index (AHI).
The thirty patients at the commencement of the study had an average AHI of 31.39 with a sample standard deviation of 12.34. After two months the AHI of each patient was again measured. The MAS treatment group experienced an average reduction in AHI of 8.69 with a sample standard deviation of 9.30. The TSD treatment group experienced an average reduction in AHI of 7.80 with a sample standard deviation of 10.65.
a)A secondary measure ("response to treatment") was defined as resolution of all symptoms or an improvement in symptoms and ≥ 50% reduction in AHI. In the MAS group 12 patients experienced a "response to treatment".
The standard error for the proportion of patients in the MAS group that experience a "response to treatment" is
0.0413
0.1033
0.1633
0.4575
b)
Constructing a 95% confidence interval by hand for the population proportion of patients in the MAS group that would experience a "response to treatment", the margin of error is
0.2024
0.2215
0.2403
0.7309
c)
In addition to the 12 patients in the MAS group who experienced a "response to treatment", 6 patients in the TSD group also experienced a "response to treatment". The standard error for the difference in the proportion of patients experiencing a "response to treatment" between the two groups is
0.0413
0.1033
0.1633
0.4575
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