a. Synthesizing glutamine is endergonic and so not spontaneous. How would having hese two reactions occur at the same time (likely by having an enzyme add a
a. Synthesizing glutamine is endergonic and so not spontaneous. How would having hese two reactions occur at the same time (likely by having an enzyme add a
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter2: Cell Physiology
Section: Chapter Questions
Problem 2SQE
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![2. One role of ATP is to facilitate reactions that would not occur spontaneously. The three
phosphate groups are electron rich and tend to repel each other. Therefore, ATP is a bit
like a compressed spring, ready to kick off one phosphate group releasing energy.
Consider:
Glutamic acid + NH3 ---> Glutamine
ATP ---> ADP + Pi
delta G= 3.4 kcal/mol
delta G= -7.3 kcal/mol
a. Synthesizing glutamine is endergonic and so not spontaneous. How would having
these two reactions occur at the same time (likely by having an enzyme add a
phosphate group from ATP to phosphorylate glutamic acid) energetically help with
glutamine production?
b. What is delta G for the combined reactions?
c. Draw a simple energy diagram (showing energy of reactants and products) that shows
why the glutamine reaction is not spontaneous. Then draw an energy diagram for the
coupled reactions that shows why the combined reaction is favorable.
d. Name a few of the biological processes in the body that require ATP?](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F69d3c8b6-4012-43b0-80a6-d85ebf5fdc33%2Fa9f2a0eb-a7da-49db-84e9-be1de1a066d7%2Fkgk01h9f_processed.png&w=3840&q=75)
Transcribed Image Text:2. One role of ATP is to facilitate reactions that would not occur spontaneously. The three
phosphate groups are electron rich and tend to repel each other. Therefore, ATP is a bit
like a compressed spring, ready to kick off one phosphate group releasing energy.
Consider:
Glutamic acid + NH3 ---> Glutamine
ATP ---> ADP + Pi
delta G= 3.4 kcal/mol
delta G= -7.3 kcal/mol
a. Synthesizing glutamine is endergonic and so not spontaneous. How would having
these two reactions occur at the same time (likely by having an enzyme add a
phosphate group from ATP to phosphorylate glutamic acid) energetically help with
glutamine production?
b. What is delta G for the combined reactions?
c. Draw a simple energy diagram (showing energy of reactants and products) that shows
why the glutamine reaction is not spontaneous. Then draw an energy diagram for the
coupled reactions that shows why the combined reaction is favorable.
d. Name a few of the biological processes in the body that require ATP?
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