Enzyme activity is dependent on many factors. List at least three different factors that could negatively impact enzyme activity and describe one use for each instance in the body. (I.E. Oxycontin binds to enzyme active sites responsible for transferring pain signals, thus would be considered a

Q: Type VI glycogen storage disease (Hers disease) is a rare metabolic disorder caused by lack of…

A: Glycogen phosphorylase is the enzyme that breaks down glycogen to glucose-1 phosphate which is then…

Q: T F T F T F T T F F T F T F Vmax is the velocity observed when all of the enzyme present is fully…

A: The kinetics of an enzyme-catalyzed reaction can be described using a variety of parameters,…

Q: Name two forms of control of enzymatic action. Which of the two is more important in control of…

A: Enzymes are specialized proteins that can catalyze biochemical reactions. Enzymes can be classified…

Q: Metformin is a commonly used treatment for type 2 diabetes. The active compound was isolated from…

A: Metformin primarily lowers blood glucose levels by reducing liver glucose production, improving…

Q: What is the rationale for the inhibition of muscle glycogen phosphorylase by glucose 6- phosphate…

A: Glycogenolysis- breaking down of molecular glycogen into glucose.  Glycolysis- glucose molecules…

Q: An adolescent male patient presented with pain in the calf muscle on exercise. On biopsy an…

A: The given clinical scenario is  suggestive of McArdle's disease.

Q: The concentration of blood glucose is approximately 5 mM. You have identified a person whose muscle…

A: Enzymes are the biological catalysts that have the ability to change the rate of metabolic reactions…

Q: Why would a deficiency in debranching enzyme be detrimental to glycogen metabolism? (Select all that…

A: Glycogen is a multibranched polysaccharide of glucose that serves as a form of energy storage in…

Q: Different control mechanisms are used to regulate the synthesis of glycogen. Match the action on the…

A: Increase in the concentration of inorganic phosphate ions: No effect on glycogen synthesis.Decrease…

Q: (a)What are the two superfamilies of proteins in which amylase is categorized? (b)To which…

A: Proteins are made up of amino acids that are linked together by peptides. Along with the R side…

Q: Describe the advantages of using triacylglycerols as the principal source of stored metabolic…

A: Fatty acids may form triacylglycerol's, which are also known as triglycerides, which are the most…

Q: n a particular enzyme, an alanine residue is located in a cleft where the substrate binds. A…

A: Mutation is the process of alteration or change in the nucleotide sequence of the DNA or the genetic…

Q: the impact of phosphorylation of glycogen phosphorylase on its heterotropic regulation.

A: The impact of phosphorylation of gylcogen phosphorylase on its heterotropic regulation…

Q: Triacylglycerols in adipose tissue do not enter the bloodstream as triacyglycerolsexplain

A: Triacylglycerols, also known as triglycerides, are a type of fat (lipid) found in your blood. A…

Q: Write a balanced equation for the hydrolysis of cyclic GMP, catalyzed by CGMP phosphodiesterase.…

A: The hydrolysis of cyclic GMP catalyzed by cGMP phosphodiesterase gives the following balanced…

Q: The glycolytic pathway is regulated by a number of key enzymes. Describe the various substrates and…

A: Introduction: The degradation of glucose into two molecules of pyruvate with the formation of ATP is…

Q: Glycogen stored in muscle and liver is used for following organs in the order: Select one: a.blood,…

A: Note: please always mention the needed parts in case of multiple questions. Thank you! Enzymes are…

Q: What is the major activator (non-allosteric, direct-activator) of phosphorylase?  How does this…

A: The entire number of biochemical processes involved in sustaining the living circumstances of cells…

Q: One    metabolic    scenario that    leads to insulin    resistance is the elevation    of the…

A: Insulin resistance is defined as the inactivity of insulin in its target cells. The examples of…

Q: Generally speaking, if glycogen phosphorylase is activated by being phosphorylated, then glycogen…

A: Glycogen metabolism: Glycogen is a polysaccharide that contains multiple glucose units and their…

Q: List reaction or pathways of fatty acid oxidation and biosynthesis affected by insulin and glucagon.

A: Insulin is the hormone synthesized by the β cells of pancreas. Whereas glucagon is synthesized by…

Q: C. What types of inhibitors of this enzyme is shown below? (1). D. What effect (increase, decrease,…

A: Enzymes are a class of protein except for ribozymes (class of ribozymes) that elevates the chemical…

Q: Describe the role of glutamine and glutamate in amino acid metabolism.

A: Glutamine: It is a non-essential amino acid as it is produced by our body. It is the primary amino…

Q: Digoxin, a toxin derived from the foxglove (shown), can be used to treat heart disorders such as…

A: Acetylcholine Is Released and Binds to Receptors on the Muscle Membrane. Open channels allow an…

Q: Can you please pick the right answer in each parentheses? Gluconeogenesis is essentially  ["a bypass…

A: Biochemical reactions involves a series enzyme-catalyzed reactions that involves the generation of a…

Q: B) Read the situations below and indicate which of the four methods of enzyme regulation is…

A: Note: We’ll answer the first question since the exact one wasn’t specified. Please submit a new…

Q: Ingesting large amounts of glucose before a marathon might seem to be a good way of increasing the…

A: Glucose is the main source of carbohydrates that gives an ample amount of energy. This energy is…

Q: Write a one-sentence explanation for each of the following statements. (a) In liver, glucagon…

A: Carbohydrate metabolism is a fundamental biochemical process that involved in a continuous supply of…

Q: UDP-glucuronosyltransferase enzymes bind the organic compound UDP-glucuronic acid (UDP-GA) in order…

A: Introduction: The major site for drug metabolism is the liver. It can be metabolized by oxidation,…

Q: Why are the enzymes α-Amylase and α-glucosidase active in a patient with hyperglycemia or diabetes?…

A: Enzymes are biological catalysts that increase the rate of the reaction that occurs inside the…

Q: Refer to the Biochemistry in Focus section of your text for this chapter to answer this question. In…

A: Glycogen metabolism is quite complex. Lots of processes occur in it such as glycogenesis,…

Q: Regulatory enzymes are crucial for the proper functioning and coordination of glycolysis and…

A: Introduction: Enzymes are the biological catalysts that increase the rate of a chemical reaction…

Q: Would you expect insulin to increase or decrease the activity of the enzyme ATP-citrate lyase?

A: The insulin is a peptide hormone produced by the beta cells of pancreatic islets. The insulin is…

Q: . Avidin is a protein that binds extremely tightly to biotin, so avidin is a potent inhibitor of…

A: The synthesis of glucose from various precursors in the body is called gluconeogenesis. Glucose is…

Q: Falling energy levels increase the cellular AMP/ATP ratio, priming AMPK for activation by the liver…

A: In order to carry out all the biological processes in the body smoothly the cells need to make…

Q: Glucose binds to glycogen phosphorylase and competitively inhibits the enzyme. What is the…

A: Glucose belongs to the category of carbohydrates and is a monosaccharide. Plants and some algae…

Q: a) Effect of mutation Y194F in glycogenenin on glycogen synthesis. b) Effect on the loss of the…

A: Glycogen synthesis and glycogen degradation are catalyzed by glycogen synthase and glycogen…

Q: You have a reaction that is very slow on its own, but is accelerated in the presence of an enzyme.…

A: 1. Enzyme increased Kcat  - Kcat is the maximal velocity of the catalyzed reaction divided by the…

Q: The inhibitory effect of an uncompetitive inhibitor is greater at high [S] than at low [S]. Explain…

A: Uncompetitive inhibition of the process in which the inhibitor gets binded to the ES complex. ES…

Q: escribe the catalytic reaction mechanism of the enzyme acetylcholinesterase. Discuss the functional…

A: Acetylcholinesterase(AChE) is an enzyme found in the synapses of nerve cells and muscle cells. This…