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a. Suggest two possible reasons why iron Fe2+ must be incorporated into the heme group, rather than free in the red blood cells? b. Both oxygen and carbon dioxide are bound to hemoglobin Hb. Where are they bound in Hb? What changes in the conformation of Hb do they cause upon binding? c. What triggers the release of 02 in Hb when red blood cells are transported into tissues?

a. Suggest two possible reasons why iron Fe2+ must be incorporated into the heme group, rather than free in the red blood cells? b. Both oxygen and carbon dioxide are bound to hemoglobin Hb. Where are they bound in Hb? What changes in the conformation of Hb do they cause upon binding? c. What triggers the release of 02 in Hb when red blood cells are transported into tissues?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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a. Suggest two possible reasons why iron Fe2+ must be incorporated into the heme group, rather than free in the red blood cells? b. Both oxygen and carbon dioxide are bound to hemoglobin Hb. Where are they bound in Hb? What changes in the conformation of Hb do they cause upon binding? c. What triggers the release of 02 in Hb when red blood cells are transported into tissues? d. Lactic acid is produced in muscle tissue during strenuous physical activity. How does lactate affect oxygen release from Hb?
Transcribed Image Text:a. Suggest two possible reasons why iron Fe2+ must be incorporated into the heme group, rather than free in the red blood cells? b. Both oxygen and carbon dioxide are bound to hemoglobin Hb. Where are they bound in Hb? What changes in the conformation of Hb do they cause upon binding? c. What triggers the release of 02 in Hb when red blood cells are transported into tissues? d. Lactic acid is produced in muscle tissue during strenuous physical activity. How does lactate affect oxygen release from Hb?
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