A scientist mutates eIF-2 to eliminate its GTP hydrolysis capability. How would this mutated form of eIF-2 alter translation? a. Initiation factors would not be able to bind to mRNA. b. The large ribosomal subunit would not be able to interact with mRNA transcripts. c. tRNAi-Met would not scan mRNA transcripts for the start codon. d. eIF-2 would not be able to interact with the small ribosomal subunit.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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A scientist mutates eIF-2 to eliminate its GTP hydrolysis
capability. How would this mutated form of eIF-2 alter
translation?
a. Initiation factors would not be able to bind to
mRNA.
b. The large ribosomal subunit would not be able to
interact with mRNA transcripts.
c. tRNAi-Met would not scan mRNA transcripts for
the start codon.
d. eIF-2 would not be able to interact with the small
ribosomal subunit.

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