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A protease binds its substrate in an extended conformation for better access to its amide linkages for hydrolysis. When this happened, which quadrant of a Ramachandran plot will the substrate's phi-psi bonds most likely be located in?

A protease binds its substrate in an extended conformation for better access to its amide linkages for hydrolysis. When this happened, which quadrant of a Ramachandran plot will the substrate's phi-psi bonds most likely be located in?

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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08:24 Tue Nov 23 90% T + : E) 10.0 5. A protease binds its substrate in an extended conformation for better access to its amide linkages for hydrolysis. When this happened, which quadrant of a Ramachandran plot will the substrate's phi-psi bonds most likely be located in? 180 120 60 -60 -120 -180 -180 180 6 (dearees) A) Southwest quadrant where y = negative and O = B) Southeast quadrant where y = negative and 0 = positive C) Northwest quadrant where = positive and 0 = negative D) Northeast quadrant where y = positive and O = positive E) In the center where O = ) =0° negative %3D %3D 3 %3D 22 6. Secondary structure is largely stabilized by hydrogen bonds ; tertiary structure is largely stabilized by the hydropnobic etlect. (WRITE your answer for BOTH blanks into the blanks above or in order on your answer sheet. Both must be correct for credit.) > ý (degrees)
Transcribed Image Text:08:24 Tue Nov 23 90% T + : E) 10.0 5. A protease binds its substrate in an extended conformation for better access to its amide linkages for hydrolysis. When this happened, which quadrant of a Ramachandran plot will the substrate's phi-psi bonds most likely be located in? 180 120 60 -60 -120 -180 -180 180 6 (dearees) A) Southwest quadrant where y = negative and O = B) Southeast quadrant where y = negative and 0 = positive C) Northwest quadrant where = positive and 0 = negative D) Northeast quadrant where y = positive and O = positive E) In the center where O = ) =0° negative %3D %3D 3 %3D 22 6. Secondary structure is largely stabilized by hydrogen bonds ; tertiary structure is largely stabilized by the hydropnobic etlect. (WRITE your answer for BOTH blanks into the blanks above or in order on your answer sheet. Both must be correct for credit.) > ý (degrees)
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