A pharmaceutical mixture consisting of 60 mass % A and the balance B. The particles are spherical. The particle density of A is 500 and that of B is 700 kg/m3. The cumulative undersize mass distributions of the two components are shown below. If samples of 1 g (corresponding to a single dose) are withdrawn from the mixture, determine the following: size (µm) 450 500 600 700 850 1000 1200 1400 1700 2100 N3A (cumulative A undersized by mass) 0 0.02 0.04 0.07 0.12 0.19 0.32 0.5 0.8 1 N3B (cumulative B undersized by mass) 0 0 0.08 0.21 0.44 0.68 0.88 1 1 1 a) total number of particles of component A in a 1 g of pure A (correct answer: 4334) b) total number of particles of component B in a 1 g of pure B (correct answer: 5338) c) expected standard deviation between the samples for a random mix of the composition in % based on number using the equation of Lacy (correct answer: 0.7559)
A pharmaceutical mixture consisting of 60 mass % A and the balance B. The particles are spherical. The particle density of A is 500 and that of B is 700 kg/m3. The cumulative undersize mass distributions of the two components are shown below. If samples of 1 g (corresponding to a single dose) are withdrawn from the mixture, determine the following: size (µm) 450 500 600 700 850 1000 1200 1400 1700 2100 N3A (cumulative A undersized by mass) 0 0.02 0.04 0.07 0.12 0.19 0.32 0.5 0.8 1 N3B (cumulative B undersized by mass) 0 0 0.08 0.21 0.44 0.68 0.88 1 1 1 a) total number of particles of component A in a 1 g of pure A (correct answer: 4334) b) total number of particles of component B in a 1 g of pure B (correct answer: 5338) c) expected standard deviation between the samples for a random mix of the composition in % based on number using the equation of Lacy (correct answer: 0.7559)
Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
Section: Chapter Questions
Problem 1.1P
Related questions
Question
A pharmaceutical mixture consisting of 60 mass % A and the balance B. The particles are spherical. The particle density of A is 500 and that of B is 700 kg/m3. The cumulative undersize mass distributions of the two components are shown below. If samples of 1 g (corresponding to a single dose) are withdrawn from the mixture, determine the following:
size (µm) |
450 500 600 700 850 1000 1200 1400 1700 2100
|
N3A (cumulative A undersized by mass) |
0 0.02 0.04 0.07 0.12 0.19 0.32 0.5 0.8 1 |
N3B (cumulative B undersized by mass) |
0 0 0.08 0.21 0.44 0.68 0.88 1 1 1 |
- a) total number of particles of component A in a 1 g of pure A (correct answer: 4334)
- b) total number of particles of component B in a 1 g of pure B (correct answer: 5338)
- c) expected standard deviation between the samples for a random mix of the composition in % based on number using the equation of Lacy (correct answer: 0.7559)
- d) expected standard deviation between the samples for a mixture in an unmixed state of the composition in % based on number using the equation of Lacy (correct answer: 48.99)
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 7 steps with 15 images
Recommended textbooks for you
Introduction to Chemical Engineering Thermodynami…
Chemical Engineering
ISBN:
9781259696527
Author:
J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:
McGraw-Hill Education
Elementary Principles of Chemical Processes, Bind…
Chemical Engineering
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY
Elements of Chemical Reaction Engineering (5th Ed…
Chemical Engineering
ISBN:
9780133887518
Author:
H. Scott Fogler
Publisher:
Prentice Hall
Introduction to Chemical Engineering Thermodynami…
Chemical Engineering
ISBN:
9781259696527
Author:
J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:
McGraw-Hill Education
Elementary Principles of Chemical Processes, Bind…
Chemical Engineering
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY
Elements of Chemical Reaction Engineering (5th Ed…
Chemical Engineering
ISBN:
9780133887518
Author:
H. Scott Fogler
Publisher:
Prentice Hall
Industrial Plastics: Theory and Applications
Chemical Engineering
ISBN:
9781285061238
Author:
Lokensgard, Erik
Publisher:
Delmar Cengage Learning
Unit Operations of Chemical Engineering
Chemical Engineering
ISBN:
9780072848236
Author:
Warren McCabe, Julian C. Smith, Peter Harriott
Publisher:
McGraw-Hill Companies, The