A non-reactive substrate analogue has been found to inhibit a target enzyme. Modifying the inhibitor to make it more like TS (‡) will? (Select All that Apply) a. Make it a better inhibitor b. Make it a worse inhibitor c. Make it bind tighter d. Make it bind weaker e. Increase the KD f. Decrease the KD
A non-reactive substrate analogue has been found to inhibit a target enzyme. Modifying the inhibitor to make it more like TS (‡) will? (Select All that Apply) a. Make it a better inhibitor b. Make it a worse inhibitor c. Make it bind tighter d. Make it bind weaker e. Increase the KD f. Decrease the KD
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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![A non-reactive substrate analogue has been found to inhibit a
target enzyme. Modifying the inhibitor to make it more like TS
(‡) will? (Select All that Apply)
a. Make it a better inhibitor
b. Make it a worse inhibitor
c. Make it bind tighter
d. Make it bind weaker
e. Increase the KD
f. Decrease the KD](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F62cafd63-1199-4bdd-af76-f04ea1816f0b%2F03639638-c1ec-4ff9-9e31-e6bc9242b0f3%2Fer0eo3_processed.jpeg&w=3840&q=75)
Transcribed Image Text:A non-reactive substrate analogue has been found to inhibit a
target enzyme. Modifying the inhibitor to make it more like TS
(‡) will? (Select All that Apply)
a. Make it a better inhibitor
b. Make it a worse inhibitor
c. Make it bind tighter
d. Make it bind weaker
e. Increase the KD
f. Decrease the KD
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