1. Suppose an enzyme only shows activity when the side chain -COOH group of a glutamic acid in the active site is protonated. It is known that the pKa of the side chain -COOH group is 4.07. a) Is the enzyme more active at pH 2.4 or 5.7? Explain. b) What percentage of the enzymes is active at pH = 6.5? Explain. c) At what pH will the enzyme show 78% of maximal activity?

1. Suppose an enzyme only shows activity when the side chain -COOH group of a glutamic acid in the active site is protonated. It is known that the pKa of the side chain -COOH group is 4.07. a) Is the enzyme more active at pH 2.4 or 5.7? Explain. b) What percentage of the enzymes is active at pH = 6.5? Explain. c) At what pH will the enzyme show 78% of maximal activity?

Chemistry

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I realllyyy need help with this one please help

1. Suppose an enzyme only shows activity when the side chain -COOH group of a glutamic acid
in the active site is protonated. It is known that the pKa of the side chain -COOH group is 4.07.
a) Is the enzyme more active at pH 2.4 or 5.7? Explain.
b) What percentage of the enzymes is active at pH = 6.5? Explain.
c) At what pH will the enzyme show 78% of maximal activity?

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