a) How many induced dipole-induced dipole interactions are present between the protein and compound A? 0 1 2 3 4 b) How many Hydrogen Bonds are present between the protein and compound A? 0 1 2 3 4 c) How many ionic bonds are present between the protein and compound A? 0 1 2 3 4 d) Which ligand binds the strongest to the binding site? A B C e) Which ligand binds the weakest to the binding site? A B C f) Briefly explain your reasoning for your answers to question (d) and (e)
a) How many induced dipole-induced dipole interactions are present between the protein and compound A? 0 1 2 3 4 b) How many Hydrogen Bonds are present between the protein and compound A? 0 1 2 3 4 c) How many ionic bonds are present between the protein and compound A? 0 1 2 3 4 d) Which ligand binds the strongest to the binding site? A B C e) Which ligand binds the weakest to the binding site? A B C f) Briefly explain your reasoning for your answers to question (d) and (e)
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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a) How many induced dipole-induced dipole interactions are present between the protein and compound A?
- 0
- 1
- 2
- 3
- 4
b) How many Hydrogen Bonds are present between the protein and compound A?
- 0
- 1
- 2
- 3
- 4
c) How many ionic bonds are present between the protein and compound A?
- 0
- 1
- 2
- 3
- 4
d) Which ligand binds the strongest to the binding site?
- A
- B
- C
e) Which ligand binds the weakest to the binding site?
- A
- B
- C
f) Briefly explain your reasoning for your answers to question (d) and (e).
Transcribed Image Text:Below is a binding site on a hormone receptor. The thick black line represents the edge of the
protein/binding site, or the space the ligand has to bind. The atoms around that indicate the
functional groups from the protein available for binding with the ligand. The binding site is shown
with 3 potential ligands bound to it.
H
HO
HO
B
H
HO
OH
NH3
HO
HO
A
OH OH
NH3
HO
HO
OH OH
HO
H₂N
CH3
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