A new method for the determination of cholesterol in serum is being developed in which the rate of depletion of oxygen is measured with an oxygen electrode upon reaction of the cholesterol with oxygen, when catalyzed by the enzyme cholesterol oxidase. a. Use Q-test and Grubb’s Test in determining if the extreme values (higher and lower) are outliers. b. Compute for the value of mean, standard deviation, and RSD for the data set (after rejecting any outliers from the Grubb’s test

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A new method for the determination of cholesterol in serum is being developed in which
the rate of depletion of oxygen is measured with an oxygen electrode upon reaction of the
cholesterol with oxygen, when catalyzed by the enzyme cholesterol oxidase.
a. Use Q-test and Grubb’s Test in determining if the extreme values (higher and
lower) are outliers.
b. Compute for the value of mean, standard deviation, and RSD for the data set (after rejecting
any outliers from the Grubb’s test)

 
53. A new method for the determination of cholesterol in serum is being developed in which the rate
of depletion of oxygen is measured with an oxygen electrode upon reaction of the cholesterol with
oxygen, when catalyzed by the enzyme cholesterol oxidase. The results for several samples are
compared with those of the standard Lieberman colorimetric method. From the following data,
determine by the t-test if there is a statistically significant difference between the two methods
and calculate the correlation coefficient. Assume the two methods have similar precisions.
Enzyme
Method (mg/dL)
Colorimetric
Sample
Method (mg/dL)
1
305
300
385
392
193
185
4
162
152
478
480
6.
455
238
461
7
232
8.
298
I
408
290
9
401
10
323
315
Transcribed Image Text:53. A new method for the determination of cholesterol in serum is being developed in which the rate of depletion of oxygen is measured with an oxygen electrode upon reaction of the cholesterol with oxygen, when catalyzed by the enzyme cholesterol oxidase. The results for several samples are compared with those of the standard Lieberman colorimetric method. From the following data, determine by the t-test if there is a statistically significant difference between the two methods and calculate the correlation coefficient. Assume the two methods have similar precisions. Enzyme Method (mg/dL) Colorimetric Sample Method (mg/dL) 1 305 300 385 392 193 185 4 162 152 478 480 6. 455 238 461 7 232 8. 298 I 408 290 9 401 10 323 315
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