A main function of the cell membrane is to be very selective as to what is able to cross through, a condition known as a ? barrier. In the fluid mosaic membrane model, lipids are organized in a ? arrangement, such that ? portions of the lipids are exposed to either the interior or exterior of the cell, while the ? lipid portions are sandwiched in the middle of the membrane.

A main function of the cell membrane is to be very selective as to what is able to cross through, a condition known as a ? barrier. In the fluid mosaic membrane model, lipids are organized in a ? arrangement, such that ? portions of the lipids are exposed to either the interior or exterior of the cell, while the ? lipid portions are sandwiched in the middle of the membrane.

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter2: Cell Physiology

Section: Chapter Questions

Problem 11RE

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A main function of the cell membrane is to be very selective as to what is able to cross through, a condition known as a barrier. In the fluid mosaic membrane model, lipids are organized in a arrangement, such that portions of the lipids are exposed to either the interior or exterior of the cell, while the lipid portions are sandwiched in the middle of the membrane. As part of the cell membrane, a main function of proteins is to provide while a main function of proteins is to provide Other cell membrane molecules include which function to provide fluidity to rigid membranes and rigidity to fluid membranes; and surface carbohydrates, which function to provide . Aminophospholipids move to the inner leaflet of the membrane, by an enzyme known as the
Besides lipid molecules, cell membranes also contain many different types of proteins, each with specific functions. In the following table, select the common type of membrane protein in the right-hand column that each statement in the left-hand column describes. The choices on the Type of Membrane Protein are the same for theFunction of the Membrane Protein
Draw a lipid bilayer, and focus on three lipids that are on the same side of the membrane. Color in the areas where you expect the hydrophobic interactions, and in another color, shade in the areas that are hydrophilic. Draw another lipid bilayer, and for this one, include two membrane proteins. One of them should be an integral membrane protein and the other one a peripheral membrane protein. Label the lipid bilayer, the side the faces the cytoplasm and the side that faces outside the cell. Also label the two proteins, and shade in the areas where you predict that you would find hydrophobic amino acids and hydrophilic amino acids.
In the "fluid " _______ cell membrane model, lipids are organized in a ________ arrangement, such that _______ portions of the lipids are exposed to either the interior or exterior of the cell, while the lipid portions are sandwiched in the middle of the membrane. As part of the cell membrane, a main function of peripheral proteins is to provide _________ , while a main function of proteins is to provide _________ . Other cell membrane molecules include a compound called __________, which functions to provide fluidity to rigid membranes and rigidity to fluid membranes; and surface carbohydrates, which function in the membrane not to provide energy, but instead to provide _________ _____ . Aminophospholipids (including PE and ) move to the inner leaflet of the membrane, by an enzyme known as the ._______ A main function of the cell membrane is to be very selective as to what is able to cross through, a condition known as a barrier.
In 2-3 sentences, summarize the spatial distribution of different types of structural lipids within cells. Of the types discussed in class, which are predominantly found on the outer leaflet of the plasma membrane, and which are more likely to be found on the interior of the cell? In your explanation, suggest a reason for this distribution.
Which one of the these primary protein structures is most likely to form an alpha helix that would would cross a plasma membrane from the extracellular side to the cytoplasmic side? The N terminus is outside the cell and the C terminus is inside the cell in this example. Use the diagram provided to decode the one letter amino acid abbreviations. Nonpolar side chains No charged or electro- negative atoms to form hydrogen bonds; not soluble in water Polar side chains Partial charges can form hydrogen bonds; soluble in water Electrically charged side chains Charged side chains form hydrogen bonds; highly soluble in water H H₂N-C-C H₂N-C- H₂N+ Glycine (G) Gly H H H₂N* Methionine (M) Met C 8*CH₂ 6 OH 2011 Pearson Education, Inc. CH₂ CH₂ S CH₂ =0 Serine (S) Ser c=0 O O Aspartate (D) Asp 20 H₂N-C- с CH₂ H₂N* HO Acidic Alanine (A) Ala H L CH C H₂N-C C CH₂ CH₂ Threonine (T Thr H₂N C Phenylalanine (F) Phe O 0=0 CH₂ CH₂ Glutamate (E) Glu ON-DTNLRRSIAGLLIRHKKE - COOH H₂N+…
For the lipids within the bilayer that comprise the plasma membrane: O The hydrophilic ends face outside (extracellular/exoplasmic face) and inside (cytoplasmic face) of the cells, with hydrophobic ends buried in the center of the lipid bilayer. The hydrophobic ends face outside (extracellular/exoplasmic face) and inside (cytoplasmic face) of the cells, with hydrophilic ends buried in the center of the lipid bilayer. The hydrophilic ends face the outside (extracellular/exoplasmic face) of the cells and the hydrophobic ends face inside (cytoplasmic face) of the cells. O Hydrophobic and hydrophilic ends face outside (extracellular/exoplasmic face) and inside (cytoplasmic face) of the cells randomly. The hydrophobic ends face the outside (extracellular/exoplasmic face) of the cells, the hydrophilic ends face inside (cytoplasmic face) of the cells.
Which of these structures would you expect to find as part of the transmembrane portion of an integral membrane protein? Structure B would be part of the transmembrane domain of an integral membrane protein. Structure C would be part of the transmembrane domain of an integral membrane protein. Structure A would be part of the transmembrane domain of an integral membrane protein.
Drawn below is a schematic of a transmembrane protein. Extracellular Cell membrane Cytosolic side (a) From the list below, select the amino acid(s) that might by more common in the extracellular domain of this membrane protein and whose side- chain can form hydrogen bonds with the surrounding water molecules. Explain why you selected this option(s). Lysine Serine Phenylalanine Methionine (b) From the list below, select the amino acid(s) that would likely be found in the transmembrane/ membrane spanning domain of this protein and whose side- chain interacts with the lipid bilayer. Lysine Serine Phenylalanine Methionine
A researcher is isolating proteins from a cell via different techniques. They find that when the cell is ground with a blender, all of the proteins in the cell can be extracted. However if instead the cell membranes are agitated in a 1.2 M KCl mixture, only about 70% of the total protein is extracted.What class of membrane proteins are in this soluble extract and what forces normally hold them to the membrane?What class of membrane proteins are the 30% of proteins that remain behind, and what forces hold these proteins in the membrane? If a solution of ionic solids was not available, what other solvent systems could be used to extract these proteins?
The plasma membrane of E. coli is about 75% protein and 25% phospholipid by weight. How many molecules of membrane lipid are present for each molecule of membrane protein? Assume an average protein Mr of 50,000and an average phospholipid Mr of 750. What more would you need to know to estimate the fraction of the membrane surface that is covered by lipids?
In the figure below, an integral membrane protein is shown. These proteins sit inside of cell membranes. Some integral proteins are membrane channels or transporters, while others serve as enzymes, receptors, or anchors. Describe the differences you would expect to see in the amino acid side chains on the outer surface of an integral cell membrane protein, as compared to a water-soluble globular protein. Be sure to discuss the chemical nature of the cell membrane in your answer.