Answered: A hydrophilic drug A.Has a high…

Phlebotomy Essentials

6th Edition

ISBN:9781451194524

Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Chapter1: Phlebotomy: Past And Present And The Healthcare Setting

Section: Chapter Questions

Problem 1SRQ

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A hydrophilic drug A.Has a high reabsorption in renal tubules B.Has a low ability to penetraye the cell membrane C.Can cross the blood brain barrier easily D.Can bind to intracellular receptors. 2.The phase 1 reaction most often performed by mixed function CYP450 hepatic microsomal enzyme is A.Glucuronidation B.Oxidation C.Reduction D.Acetylation 3.CYP1A2 is involved in the metabolizing of several clinically important xenobiotics such as A.Caffeine B.Morphine C.Aspirin D.Alcohol 4.Drug metabolism,the drug.......undergoes phase 2(acetylation)before undergoing phase 1 (hydrolysis) metabolic reactions A Aspirin B.Codeine C.Isoniazid D.Diazepam E.Phenytoin 5.Which of the following statements is/are true regarding the oxidation of aromatic rings A.Electron donating substituents promote oxidationat the meta position B.Electron withdrawing substituents promote oxidation at the meta position C.All aromatic rings in a molecule are hydroxylated D Monosubstituted aromatic rings can be hydroxylated at any position. When taking methylprednisolone........must be avoided as it will inhibit the metabolism of this drug A Meat B.Grapefruit C.Sugar D.Bananas 7. Adverse effects of acetaminophen include A.Liver damage B.Gastrointestinal bleeding C.Vomiting D.Sedation

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