(a) Given and Scara were given a task of synthesising (2-methylprop-1- envl)cyclohexane 2 (A potential TB drug). After a brief discussion with each other, Given proposed Method A to synthesise 2 from cyclohexanecarbaldehyde 1 while Scara proposed Method B that started from hydroxymethylcyclohexane 3. When designing a synthetic route for drug molecule, you have to make sure the synthetic process is as efficient as possible (e.g. few synthetic steps, mostly making one product and more). www. THF A Ph Ph Ph B 3 1. PCC 2. isopropyl magnesium vromide 3. H₂SO4 100 °C OH After analyzing both of these methods, draw any one possible alkene product other than (2-methylprop-1-enyl)cyclohexane 2?

(a) Given and Scara were given a task of synthesising (2-methylprop-1- envl)cyclohexane 2 (A potential TB drug). After a brief discussion with each other, Given proposed Method A to synthesise 2 from cyclohexanecarbaldehyde 1 while Scara proposed Method B that started from hydroxymethylcyclohexane 3. When designing a synthetic route for drug molecule, you have to make sure the synthetic process is as efficient as possible (e.g. few synthetic steps, mostly making one product and more). www. THF A Ph Ph Ph B 3 1. PCC 2. isopropyl magnesium vromide 3. H₂SO4 100 °C OH After analyzing both of these methods, draw any one possible alkene product other than (2-methylprop-1-enyl)cyclohexane 2?

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

What is the possible unknown compound based on the data below, please give detailed explanation on why it is the compound and also give detailed explanation on each of the other compounds
I need d,e ,f . In addition: name all of the compound in the synthesis pathway solution.
(b) Alkene 6 undergoes the reaction sequence shown below to generate 7, answer ALL parts (i) to (iii) 1) Hg(OAc)2, H₂O 2) NaBH4 7 (C11H14O) 6 (i) Identify compound 7 and give a mechanism for the reaction with Hg(OAc)2 and water. [A mechanism for the reaction with NaBH4 is not required] (ii) With reference to your mechanism, explain the regioselectivity of the reaction. (iii) What would the product be if the second step was performed using deuterated sodium borohydride (NaBD4).
(a) Give reasons :(i) CH3—CHO is more reactive than CH3COCH3 towards HCN.(ii) 4-nitrobenzoic acid is more acidic than benzoic acid.(b) Describe the following :(i) Acetylation (ii) Cannizzaro reaction (iii) Cross aldol condensation
(17). Subject :- Chemistry
Detailed mechanism of reaction of compound 5 with phosphorous tribromide to give compound 3
2. Do the following synthesis: (a) Benzene to p-t-butylbenzoic acid (b) Benzene to 1,3-dipropylbenzene (c) Benzene to p-nitrobenzoic acid (d) Benzene to p-bromobenzaldehyde (e) Acetopheneone to 1,3-diethylbenzene