A drug follows linear one compartment pharmacokinetics, ke = 0.14 hr¹ and volumeof distribution 18 L.• Calculate a suitable i.v. bolus dose to maintain plasma drug concentrations above 6mg/L for 8 hours. What is the initial plasma concentration? (C)• What is half life of this drug? (t1/2)Please select one:a.C-16.5 mg/L t1/2=5 hb.C=14 mg/L 11/2=2.5 hc.C=17.5 mg/L 11/2=3 hd.C=20.6 mg/L t1/2=5 he.C-18.4 mg/L t1/2=5 h

Pharmacokinetics involves study of a science branch where kinetics of a drug like absorption,…

Answered: A drug follows linear one compartment…

Similar questions

SOLVE THE FOLLOWING PROBLEMS OF DOSE CALCULATION, SHOW THE CALCULATIONS FOR EACH OF THEY. A. Atropine is given in doses of .5mg/kg. How much will a patient who weighs 3.5 lbs receive? B. A sick patient weighs 3.5kg, you should give him 20mg/lb of a QID drug. what is the dose total?
2. A 70-kg male subject was given 150 mg of a drug by IV injection. Blood samples were removed and assayed for intact drug. Calculate the slopes and intercepts of the three phases of the plasma level-time plot from the results tabulated below. Give the equation for the curve. Download (.pdf)|Print Time (hours) 0.17 0.33 0.50 0.67 1.00 1.50 2.00 C(μg/mL) 36.2 34.0 27.0 23.0 20.8 17.8 16.5 Time (hours) 3.0 4.0 6.0 7.0 18.0 23.0 C(ug/mL) 13.9 12.0 8.7 7.7 3.2 2.4
What are the safety guidelines for vincristine preparation and administration? A. Use an infusion pump to administer intravenously over 25-50 minutes. B. Prepare in a minibag and infuse intravenously over 5-15 minutes. C. Dilute in a 10ml syringe with normal saline and administer IV push. D. Reconstitute in a minibag of 5% dextrose in water and administer IV push.
Drug A has the concentrations indicated below in the blood following intravenous administration. From these data calculate the half-life (t1/2) of Drug A is: Drug A Concentrations Time After Intravenous Administration μg/mL of drug A in blood 2 hours 100 6 hours 25 10 hours 6.25 14 hours 1.56
An 84 year old male patient has been given a loading dose of digoxin of 298 micrograms in divided doses by intravenous infusion. He has a creatinine clearance (Ccr) of 34 ml / min. What is the maintenance dose (in micrograms) that this patient should receive? Round your answer to the nearest whole number. Use the formula provided to calculate the maintenance dose. Maintenance Dose = Peak body stores x % daily loss 100 Where: Peak Body Stores = Loading Dose % Daily Loss = 14 + Creatinine clearance (Ccr) 5
Acute lymphatic leukemia can respond well to methotrexate given 2 1/2 mg per kilogram every 14 days by IV rounding to the nearest whole number. What would be the appropriate dosage of methotrexate to administer biweekly to a patient weighing 110 pounds?
Do not include zeros at the end of decimal numbers. The problems and drug orders are presented for practice only, and actual prescribed dosages will vary according to a patien factors. Order: penicillin G potassium 2,000,000 units IM q.8h Supply: 5,000,000 units Directions: Reconstitute with 18.2 mL for 250,000 units/mL; 8.2 mL for 500,000 units/mL; 3.2 mL for 1,000,000 units/mL mL for units/mL Reconstitute with Give: mL A Moving to another question will save this response. Type here to search Esc F2 OE F4 • F5 H9 F6 DELL [ d P F10
A 16 year old boy has been prescribed the cytotoxic medication fludarabine 10mg film coated tablets at a dose of 30mg/m2 for ten days. The patient weighs 60 kg and is 1.60 m tall. Bodysurfacearea(m2)=weight(kg)xheight(cm)3600 How many 10 mg capsules are required to provide the 10 day course of treatment? units = capsules
Analgesia plan for a cat with urinary obstruction: Buprenorphine (for pain) 4.54kgx0.03mg/kg =0.1362mg÷0.3mg/ml=0.45ml Meloxicam (Anti-inflammatory): 4.54 kg x 0.3 mg/kg = 1.3662 mg ÷ 5 mg/ml = 0.27 ml * Please calculate for 4 days, since the cat will remain in the hospital for 4 days.
Please show dimensional analysis to solve
An order reads: Daptomycin in NS IV Administer 8 mg/kg over 30 min q24 hrs x 10 days How many milliliters of a vial containing 500 mg of daptomycin in 10 mL should be added to a 100 mL bag of NS to follow the order above to treat a 245-lb patient?
Sarah who weighs 67 kg is to receive acetylcysteine at a dose of 50 mg/kg infused over 4 hours for paracetamol overdose. The required volume of concentrated acetylcysteine solution (200 mg/mL) has been added to 500 mL of 5% glucose solution. What is the concentration of the solution to be infused (mg/mL)? (Answer to 1 decimal place.) Answer: 16.75 mg x

SEE MORE QUESTIONS