2. A 70-kg male subject was given 150 mg of a drug by IV injection. Blood samples were removed and assayed for intact drug. Calculate the slopes and intercepts of the three phases of the plasma level-time plot from the results tabulated below. Give the equation for the curve. Download (.pdf)|Print Time (hours) 0.17 0.33 0.50 0.67 1.00 1.50 2.00 C(μg/mL) 36.2 34.0 27.0 23.0 20.8 17.8 16.5 Time (hours) 3.0 4.0 6.0 7.0 18.0 23.0 C(ug/mL) 13.9 12.0 8.7 7.7 3.2 2.4
2. A 70-kg male subject was given 150 mg of a drug by IV injection. Blood samples were removed and assayed for intact drug. Calculate the slopes and intercepts of the three phases of the plasma level-time plot from the results tabulated below. Give the equation for the curve. Download (.pdf)|Print Time (hours) 0.17 0.33 0.50 0.67 1.00 1.50 2.00 C(μg/mL) 36.2 34.0 27.0 23.0 20.8 17.8 16.5 Time (hours) 3.0 4.0 6.0 7.0 18.0 23.0 C(ug/mL) 13.9 12.0 8.7 7.7 3.2 2.4
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![2. A 70-kg male subject was given 150 mg of a drug by IV injection. Blood samples were removed and
assayed for intact drug. Calculate the slopes and intercepts of the three phases of the plasma level-time
plot from the results tabulated below. Give the equation for the curve.
Download (.pdf)|Print
Time (hours)
0.17
0.33
0.50
0.67
1.00
1.50
2.00
C(μg/mL)
36.2
34.0
27.0
23.0
20.8
17.8
16.5
Time (hours)
3.0
4.0
6.0
7.0
18.0
23.0
C(ug/mL)
13.9
12.0
8.7
7.7
3.2
2.4](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F05c9b6fe-419e-4dea-bb9f-a69a7e5d242f%2F892bd60f-0ffd-49ba-8142-92274ac0e9cf%2Fzl338h_processed.png&w=3840&q=75)
Transcribed Image Text:2. A 70-kg male subject was given 150 mg of a drug by IV injection. Blood samples were removed and
assayed for intact drug. Calculate the slopes and intercepts of the three phases of the plasma level-time
plot from the results tabulated below. Give the equation for the curve.
Download (.pdf)|Print
Time (hours)
0.17
0.33
0.50
0.67
1.00
1.50
2.00
C(μg/mL)
36.2
34.0
27.0
23.0
20.8
17.8
16.5
Time (hours)
3.0
4.0
6.0
7.0
18.0
23.0
C(ug/mL)
13.9
12.0
8.7
7.7
3.2
2.4
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