a) As a gene drive that disrupts a section of the doublesex gene successfully moves through a mosquito population, would you expect the heterozygosity (H) value for the population to increase or decrease at the doublesex locus? Why? b) Gene drives work well in laboratory trials, but there remain many concerns about their ability to function within the context of natural populations. Of particular relevance is whether species can eventually evolve resistance to the introduced gene drive. You are monitoring an experiment with a gene drive designed to delete a section of doublesex in mosquitos and notice that after a few months the emergence of a resistant subpopulation. Matings between the offspring of a resistant parent and a homozygous gene drive-containing parent lead to a typical Mendelian inheritance pattern in subsequent offspring. Sequencing verifies that the gene drive itself has not changed. Propose and briefly justify one hypothesis detailing the nature of the mutation in the resistant population and how it led to this outcome.

a) As a gene drive that disrupts a section of the doublesex gene successfully moves through a mosquito population, would you expect the heterozygosity (H) value for the population to increase or decrease at the doublesex locus? Why? b) Gene drives work well in laboratory trials, but there remain many concerns about their ability to function within the context of natural populations. Of particular relevance is whether species can eventually evolve resistance to the introduced gene drive. You are monitoring an experiment with a gene drive designed to delete a section of doublesex in mosquitos and notice that after a few months the emergence of a resistant subpopulation. Matings between the offspring of a resistant parent and a homozygous gene drive-containing parent lead to a typical Mendelian inheritance pattern in subsequent offspring. Sequencing verifies that the gene drive itself has not changed. Propose and briefly justify one hypothesis detailing the nature of the mutation in the resistant population and how it led to this outcome.

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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