A 15 amino acid unit polypeptide, a billion-dollar industry polypeptide known as Kugakinin, which enhances memory power tremendously for those who take organic chemistry finals.  A complete hydrolysis (6M HCl, reflux 24 hours) of kugakinin gave following amino acids: 3Gly, 2Ser, 3Ala, 2Phe, Leu, Arg, Tyr, Val, Pro DNFB test showed Gly and Carboxypeptidase showed Ala. Partial hydrolysis gave following di and tri peptides. Gly.Ala + Ala.Phe + Phe.Gly + Gly.Leu.Arg +Arg.Ser + Ser.Tyr +Tyr.Phe + Phe.Val.Ala + Ala.Gly.Pro + Gly.Pro + Pro.Ser + Ser.Ala Please find the sequence of this wonder drug.

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
icon
Related questions
icon
Concept explainers
Question

A 15 amino acid unit polypeptide, a billion-dollar industry polypeptide known as Kugakinin, which enhances memory power tremendously for those who take organic chemistry finals.  A complete hydrolysis (6M HCl, reflux 24 hours) of kugakinin gave following amino acids:

3Gly, 2Ser, 3Ala, 2Phe, Leu, Arg, Tyr, Val, Pro

DNFB test showed Gly and Carboxypeptidase showed Ala.

Partial hydrolysis gave following di and tri peptides.

Gly.Ala + Ala.Phe + Phe.Gly + Gly.Leu.Arg +Arg.Ser + Ser.Tyr +Tyr.Phe + Phe.Val.Ala + Ala.Gly.Pro + Gly.Pro + Pro.Ser + Ser.Ala

Please find the sequence of this wonder drug.

Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps

Blurred answer
Knowledge Booster
Proteins
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY