practice problem genetics #d-fleet01-xythos.content.blackboardcdn.com/blackboard.learn.xythos.prod/5a3683e2386d2/11826556?X-Blackboard-S3-Bucket-bla3K7. A portion of a wild-type protein is shown below:-His- Thr- Glu-Asp- Trp- Leu- His- Gln- Asp-An altered form is shown below:1_12_2021-His- Asp- Arg- Gly- Leu- Ala- Thr- Ser- AspC2 17 | - 125% + »S4A) What type of mutation has occurred to convert the wild-type to a mutant protein?Where has the mutation taken place (indicate on the mRNA)?B) Draw the wild-type and the mutant mRNA molecules, and indicate the location andtype of mutation on the mRNA molecules.GSearch or type URL%45^6&7C☆*8Bb Genetics+0 ۔93)-O0

Name: practice problem genetics #d-fleet01-xythos.content.blackboardcdn.com/
Uploaded: 2024-03-20T06:42:55.000Z
Channel: Bartleby
Description: practice problem genetics #d-fleet01-xythos.content.blackboardcdn.com/blackboard.learn.xythos.prod/5a3683e2386d2/11826556?X-Blackboard-S3-Bucket-bla3K7. A portion of a wild-type protein is shown below:-His- Thr- Glu-Asp- Trp- Leu- His- Gln- Asp-An al

A mutation is a change in the sequence of DNA (or RNA in the case of some viruses) that can alter the genetic information or code of an organism. Mutations can occur naturally and spontaneously, and they can be caused by various factors, including errors during DNA replication, exposure to radiation, chemicals, or environmental factors. Mutations can occur in various parts of the genome, such as genes, regulatory regions, or non-coding regions.A) The mutation that has occurred to convert the wild-type protein to the mutant protein appears to be a point mutation, specifically a substitution mutation. In this case, one nucleotide has been changed in the DNA sequence, leading to the alteration of a single amino acid in the protein. The specific type of substitution mutation is a missense mutation, where one amino acid is replaced by another in the protein sequence.To determine the location of the mutation on the mRNA, need to look at the codons in the mRNA sequence that correspond to the altered amino acids by analyzing the sequences:-Wild Type mRNA:- His-Thr-Glu-Asp-Trp-Leu-His-Gln-AspMutant mRNA:- His-Asp-Arg-Gly-Leu-Ala-Thr-Ser-AspThe mutation has occurred at the second codon (from Thr to Asp) in the mRNA sequence. This means the mutation occurred in the DNA sequence at the second base of the codon that codes for threonine, leading to the substitution of threonine (Thr) with aspartic acid (Asp).B) The wild-type and mutant mRNA molecules with the location and type of mutation indicated:-Wild Type mRNA:- His-Thr-Glu-Asp-Trp-Leu-His-Gln-AspMutant mRNA:- His-Asp-Arg-Gly-Leu-Ala-Thr-Ser-AspLocation of Mutation:- The mutation has occurred in the second codon of the mRNA sequence.Type of Mutation:- The mutation is a point mutation, specifically a missense mutation, where threonine (Thr) has been replaced by aspartic acid (Asp) at the second codon.The DNA sequence would also have a corresponding point mutation at the second base of the codon, which ultimately led to the change in the mRNA sequence and, consequently, the protein sequence.