Please answer all parts of the question, thank you 6. The following transformation occurs by a sequence of two reactions. First aconjugate substitution occurs then a nucleophilic aromatic substitution.NH₂Fy IOEtNEt3heat(A) Propose a mechanism for this transformation.`NOEt(B) Propose why the conjugate substitution occurs prior to the nucleophilicaromatic substitution rather than the other way around.(C) Predict if the nucleophilic aromatic substitution would proceed better or worseif an iodide was used instead of the fluoride as a leaving group.

Basic concepts for this question.

6. The following transformation occurs by a sequence of two reactions. First a conjugate substitution occurs then a nucleophilic aromatic substitution. F OEt NH₂ NEt3 heat (A) Propose a mechanism for this transformation. OEt (B) Propose why the conjugate substitution occurs prior to the nucleophilic aromatic substitution rather than the other way around. (C) Predict if the nucleophilic aromatic substitution would proceed better or worse if an iodide was used instead of the fluoride as a leaving group.

6. The following transformation occurs by a sequence of two reactions. First a conjugate substitution occurs then a nucleophilic aromatic substitution. F OEt NH₂ NEt3 heat (A) Propose a mechanism for this transformation. OEt (B) Propose why the conjugate substitution occurs prior to the nucleophilic aromatic substitution rather than the other way around. (C) Predict if the nucleophilic aromatic substitution would proceed better or worse if an iodide was used instead of the fluoride as a leaving group.

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter21: Nas: Nucleophilic Aromatic Substitution

Section: Chapter Questions

Problem 8E

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