5. The enantiomers of 1-amino-2-propanol were separated and recovered as their hydrochloride salts: CH3CHCH2NH3" cr ÓH The sample of (R)-(-)-1-amino-2-propanol hydrochloride had [a]p²s -31.5° (c 0.01; methanol), and that of (S)-(+)-1-amino-2-propanol hydrochloride had [a]p²5 +35° (c 0.01; methanol). (a) Write correct stereochemical formulas for both isomers. (b) Which enantiomer was recovered with the higher purity? (c) Assuming that the optical rotation observed for the enantiomer of higher purity is the correct specific optical rotation for the compound, what is the enantiomeric excess in the sample of the other enantiomer? What is its enantiomeric composition?
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
![5. The enantiomers of 1-amino-2-propanol were separated and recovered as their
hydrochloride salts:
CH3CHCH2NH3" cr
ÓH
The sample of (R)-(-)-1-amino-2-propanol hydrochloride had [a]p²s -31.5° (c 0.01; methanol),
and that of (S)-(+)-1-amino-2-propanol hydrochloride had [a]p²5 +35° (c 0.01; methanol).
(a) Write correct stereochemical formulas for both isomers.
(b) Which enantiomer was recovered with the higher purity?
(c) Assuming that the optical rotation observed for the enantiomer of higher purity is the
correct specific optical rotation for the compound, what is the enantiomeric excess in the
sample of the other enantiomer? What is its enantiomeric composition?](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F6a0fb5d9-3f9b-48fb-9306-565befbe237b%2Ff2cdecbc-a3a7-4cc4-9108-6965d0ae262d%2Fjpqurtt.png&w=3840&q=75)
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