4. what is the antihypertensive pharmacology of the ace inhibitors?
Q: 5) Explain the synthesis, release and pharmacology of histamine
A: Histamine is a biogenic amine that is produced from the amino acid histidine and is present in many…
Q: What kind of inhibitor is GMP-PCP?
A: Inhibitors are substances with the ability to reduce the or completely stop the activity of a enzyme…
Q: RNSG Pharmacology 45. Side effects of Metoproclamide
A: The medicine methoclopramide is a member of the dopamine receptor antagonists pharmacological class.…
Q: To the right is a schematic diagram of site in the Michaelis complex of a-chy- motrypsin and a…
A: Chymotrypsin is a protease that cleaves a peptide at the C-terminal of aromatic amino acids like…
Q: 3. In this question you can do the graphs on your computer. A, Calculate the Vmax and Km in the…
A: Enzyme catalysed reactions follow Michaelis Menton equation which is : Vo=VmaxSKm + [S] Here, Vo is…
Q: Why have the chemical structure of some antimicrobial drugs been modified into semisynthetics?
A: Many antibiotics or antimicrobial drugs halt bacterial infection by interfering with the…
Q: 6. If inhibitor X changes lactase activity to a Vo of 0.333333333333 mM per minute when [S] = 2.0…
A: Michaelis and Menten derived a law in the field known as Enzyme Kinetics in 1913. They formulated an…
Q: ) i. Why is it hard to rinse out soap with rain water? ii. Discuss 3 effects of enzymatic…
A: Water can be present in two forms, viz. Hard water and Soft water. water is considered hard or soft…
Q: Describe shunting inhibition. What is the cellular mechanism, and how does it cause inhibitory…
A: Shunting is a neuronal event that happens when an excitatory postsynaptic potential and an…
Q: Sequentially list the signal transduction process from ligand binding to biological response for the…
A: Phospholipase C (PLC) is a class of enzymes that cleave the membrane phospholipids at the position…
Q: What are common adverse effects of chlorothiazide?
A: By lowering the body's sodium and water levels, the drug chlorothiazide is used to treat edoema…
Q: The Lineweaver-Burk plots in this figure represent the activities of enzymes in the absence and…
A: Inhibition : Compound which converts the enzyme into inactive substance and adversly effect the rate…
Q: structure so they can which below, II. While there are many different types of inhibitors, most have…
A: Hello! Thank you for the question. Since we do not have the information regarding the amino acid…
Q: What type of reversible inhibitor are sulfanomides? Competitive Uncompetitive…
A: Substrate molecules get converted to product molecules during a biochemical reaction. Enzymes are…
Q: From the data, do you consider [³H]-flunitrazepam to be an appropriate radiollgand epino cite of the…
A: Yes binding shows at GABA A receptor
Q: What is the significance of the different diameters of zones of inhibition?
A: A Zone of Inhibition (ZOI) test is a simple approach to measure a treated product's or surface's…
Q: What are prodrugs? How is the therapeutic effect of a prodrug affected by enzyme inhibition and…
A: Prodrugs undergo a transformation before exhibiting its pharmacological effects. They comprise…
Q: 5.Aspirin isthedrug,used for the decreasing ofinflammatory reaction and temperature. 1)Describe the…
A: Introduction NSAIDS are act as analgesic Antipyretic and anti inflammatory. these drug inhibit the…
Q: Explain the relationship between the minimum inhibitory concentrationand the therapeutic index. What…
A: Microorganisms are resistant or susceptible to antimicrobial drugs. It can be determined by drug…
Q: List the uses and side effects for Chlorpromazine
A: Chlorpromazine is an antipsychotic drug. It is used as a treatment option of various mental…
Q: State and describe the three different types of inhibitors which are competetive, uncompetetive and…
A: Introduction Enzymes are also known as biocatalysts. Enzyme increases the rate of a chemical…
Q: Explain this quesiton in descrition format whether non-barbiturate drug classes are labeled at a…
A: Non-barbiturates: Imagine a bunch of different keys, each one designed to fit into a specific (lock…
Q: 1.Substituents exhibit strong steric repulsion at the GABAA receptor ？what does it means？？ 2.…
A: Benzodiazepines are the class of compounds that are used as muscle relaxants, hypnotics,…
Q: Describe the mechanism of action of an ACE inhibitor. Based on this mechanism, when would ACE…
A: Ace inhibitors have important role in RAAS system Liver screats angiotensinogen harmone and…
4. what is the antihypertensive pharmacology of the ace inhibitors?
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- 1 What's true about Purdue Pharma and OxyContin? (Select all that apply] O OxyContin is an opioid painkiller introduced to the U.S. by Purdue in 1996 as a 12-hour timed-release dosage of oxycodone. O By crushing or dissolving the 12-hour pills, drug abusers could ingest the entire dose at one time, thus causing fatal overdoses, The Sackler-family-owned Purdue Pharma, maker of OxyContin, used unethical marketing practices. Such practices led Purdue to become the major contributor to the opiold crisis that caused the deaths of 400,000 individuals, CPurdue's aggressive marketing of OxyContin included visiting doctors, paying for their meals and travel, providing gifts, and funding pain treatment groups. M Purdue has earned in excess of $30 billion since OxyContin arrived on the market. ASome of the company's marketing messages minimized the potential for OxyContin to lead to addiction, for which it paid over $600 million in fines in 2007. Purdue announced in September 2019 that it had…1.With the data shown below, please answer the following: A. Which of the two inhibitors is more efficient at high substrate concentrations? At low substrate concentrations? Explain you reasoningPharmacology RNSG-1301 30. What patient safety considerations should be included for a client taking dornase alfa?
- List the major classes of psychedelic drugs presented in chapter 8 of Julien's Primer of Drug Action and the respective mechanisms of action that differentiate them?Please don't provide handwriting solutionexplain why A liposome of 1;1 molar ratio of cholesterol to phospholipids will be the optimum combination for the highest concentration of drug entrapment’
- 5.Myasthenia (muscle weakness)is characterized by damage in the transmission of neurotic impuise and decreased amount of acetylcholine due to autoimmune mechanisms. Prozerine is used for treatment of this disease.Specify the mechanism of this drug action. For this: 1)Write the reaction of acetylcholine degradation at neuromuscular junction. 2)What enzyme will be inhibited with prozerine? Name the class of this enzyme. 3)What is the mechanism of this enzyme inhibition?1. Start with the Michaelis-Menten equation and convert it to a double-reciprocal equation. Show how you would make a linear Lineweaver-Burk plot using this equation. 2. Based on th chart make a Lineweaver-Burk plot and later use the plot to complete the information in the table.Determine the minimum inhibitory concentrations (MIC) for compounds 1, 2, and 3 based on the microdilution results.