3a)Amides are moderately acidic at the N atom, so theycan be alkylated in a fashion that is quite similar to thealkylation of ketones and aldehydes. Predict the productof the reaction shown here, and draw its complete,detailed mechanism.1. NaH2.?3b)If in Step 2 above, the allylic chloride is replaced by another electrophile - Me-SiCl- a different product forms. Predict what this product is & draw the mechanism.Hint: the formation of Si-O bonds is very thermodynamically favorable.

The compound in which -CO-NH- bond linkage is present is known as an amide. NaH acts as a base and…

3a) Amides are moderately acidic at the N atom, so they can be alkylated in a fashion that is quite similar to the alkylation of ketones and aldehydes. Predict the product of the reaction shown here, and draw its complete, detailed mechanism. N 1. NaH 2. CI ? 3b) If in Step 2 above, the allylic chloride is replaced by another electrophile - Me-SiCl - a different product forms. Predict what this product is & draw the mechanism. Hint: the formation of Si-O bonds is very thermodynamically favorable.

3a) Amides are moderately acidic at the N atom, so they can be alkylated in a fashion that is quite similar to the alkylation of ketones and aldehydes. Predict the product of the reaction shown here, and draw its complete, detailed mechanism. N 1. NaH 2. CI ? 3b) If in Step 2 above, the allylic chloride is replaced by another electrophile - Me-SiCl - a different product forms. Predict what this product is & draw the mechanism. Hint: the formation of Si-O bonds is very thermodynamically favorable.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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