30. The shown structure is a cyclic D-monosaccharide. Which of the following statements is true? Носиг H H OH он OH CH₂OH A. The chemical can react with methanol to form a hemiacetal in solution without forming an open chain structure B. The chemical needs to form an open chain structure to be able to react with methanol to produce a glycosidic linkage in solution C. Both A and B D. Neither A nor B

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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**Question 30: The shown structure is a cyclic D-monosaccharide. Which of the following statements is true?**

**Molecular Structure Explanation:**
The diagram presents a cyclic D-monosaccharide. It features a five-membered ring with an oxygen atom. Attached to the ring are various hydroxyl (OH) groups and hydrogen (H) atoms. Specifically, the carbon atoms in this cyclic structure are bonded as follows:
- The first carbon is bonded to a hydroxymethyl group (HOCH2).
- The second carbon is bonded to an oxygen atom and a hydrogen atom.
- The third and fourth carbons both have hydroxyl groups connected to hydrogen atoms.
- The fifth carbon has a hydroxyl group and a hydrogen atom, along with a terminal methanol group (CH2OH).

**Statements to Evaluate:**
A. The chemical can react with methanol to form a hemiacetal in solution without forming an open chain structure.
B. The chemical needs to form an open chain structure to be able to react with methanol to produce a glycosidic linkage in solution.
C. Both A and B.
D. Neither A nor B.

**Explanation:**
In the context of chemical reactions, particularly those involving carbohydrates and methanol, consider the following:
- **Hemiacetal Formation (Statement A):** Hemiacetals generally form when an alcohol reacts with an aldehyde or ketone; in the case of this cyclic monosaccharide, it can already behave as a hemiacetal due to its structure.
- **Glycosidic Linkage Formation (Statement B):** For glycosidic linkages, it typically involves an open-chain form undergoing a reaction with an alcohol to form an acetal, highlighting the necessity for an open-chain structure.

Hence, after analyzing the given chemical structure and the nature of its reactions:
- It can be seen that option **B** is correct.

**Correct Answer:**
B. The chemical needs to form an open chain structure to be able to react with methanol to produce a glycosidic linkage in solution.
Transcribed Image Text:**Question 30: The shown structure is a cyclic D-monosaccharide. Which of the following statements is true?** **Molecular Structure Explanation:** The diagram presents a cyclic D-monosaccharide. It features a five-membered ring with an oxygen atom. Attached to the ring are various hydroxyl (OH) groups and hydrogen (H) atoms. Specifically, the carbon atoms in this cyclic structure are bonded as follows: - The first carbon is bonded to a hydroxymethyl group (HOCH2). - The second carbon is bonded to an oxygen atom and a hydrogen atom. - The third and fourth carbons both have hydroxyl groups connected to hydrogen atoms. - The fifth carbon has a hydroxyl group and a hydrogen atom, along with a terminal methanol group (CH2OH). **Statements to Evaluate:** A. The chemical can react with methanol to form a hemiacetal in solution without forming an open chain structure. B. The chemical needs to form an open chain structure to be able to react with methanol to produce a glycosidic linkage in solution. C. Both A and B. D. Neither A nor B. **Explanation:** In the context of chemical reactions, particularly those involving carbohydrates and methanol, consider the following: - **Hemiacetal Formation (Statement A):** Hemiacetals generally form when an alcohol reacts with an aldehyde or ketone; in the case of this cyclic monosaccharide, it can already behave as a hemiacetal due to its structure. - **Glycosidic Linkage Formation (Statement B):** For glycosidic linkages, it typically involves an open-chain form undergoing a reaction with an alcohol to form an acetal, highlighting the necessity for an open-chain structure. Hence, after analyzing the given chemical structure and the nature of its reactions: - It can be seen that option **B** is correct. **Correct Answer:** B. The chemical needs to form an open chain structure to be able to react with methanol to produce a glycosidic linkage in solution.
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