3. Researchers are investigating a newly discovered condition that greatly increases the likelihood of lung damage associated with the use of e-cigarettes. They found that 2% of their study population has the condition. The researchers believe they have found a useful marker locus for assessing the presence of the condition in individuals with unknown family history. They have found that, of those individuals with the condition, 99% have the marker allele M1. Of those without the condition, 99.8% have an alternative allele M2 at the marker locus. What is the probability that an individual has the condition if they have marker allele M1 and what do you conclude about the utility of the marker locus for indirect diagnosis?
3. Researchers are investigating a newly discovered condition that greatly increases the likelihood of lung damage associated with the use of e-cigarettes. They found that 2% of their study population has the condition. The researchers believe they have found a useful marker locus for assessing the presence of the condition in individuals with unknown family history. They have found that, of those individuals with the condition, 99% have the marker allele M1. Of those without the condition, 99.8% have an alternative allele M2 at the marker locus. What is the probability that an individual has the condition if they have marker allele M1 and what do you conclude about the utility of the marker locus for indirect diagnosis?
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