sickle cell anemia is due to a recessive allele. in a population of 1000 individuals 35 have sickle cell anemia approximately how many carriers are present in this population

Sickle cell anemia is an inheritable red blood cell disorder that results in sickle-shaped red blood cells. The sickle-shaped red blood cells can stick to blood vessel walls and cause a blockage or slow the movement of blood throughout the body.   Individuals who are heterozygous produce both normal and sickle-shaped red blood cells which gives them resistance to malaria but they do not develop sickle cell anemia (so heterozygotes are unaffected on the pedigree).Let HbS be the allele for sickle cell anemia and let HbA be the allele for normal red blood cells. Which of the following rows provides the correct genotypes for individuals I-2, I-4, II-1, and III-1? Select one: a. I-2 I-4 II-1 III-1 HbA_ HbAHbS HbAHbS HbA_ b. I-2 I-4 II-1 III-1 HbA_  HbAHbS HbAHbS HbAHbS c. I-2 I-4 II-1 III-1 HbAHbS HbAHbS HbAHbS HbAHbS d. I-2 I-4 II-1 III-1 HbAHbA HbAHbA HbAHbA HbAHbA

Define the allele associated with this form of anemia, and define the NORMAL allele of this same gene. Be sure to indicate which is which.

Sickle cell disease (SCD) affects millions of people throughout the world; the CDC "Centers for Disease Control and Prevention" estimated that in the United States: SCD affects approximately 100,000 Americans. SCD occurs among about 1 out of every 365 Black or African-American births. SCD occurs among about 1 out of every 16,300 Hispanic-American births. About 1 in 13 Black or African-American babies is born with sickle cell trait (SCT). What do sickle cells mean? And how does this disease affect the human body? Why do Some experts state it can have some benefits?

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Sickle cell anemia is caused by the sickle cell allele (HbS) of a gene that contributes tohemoglobin (Hb) production. The abnormal hemoglobin (hemoglobin-S) produced causes redblood cells to become deformed and block capillaries; tissue damage results. Affected individualshomozygous for the sickle cell gene rarely survive to reproductive age. Heterozygous individualsproduce both normal hemoglobin and a small percentage of hemoglobin-S. These individualsare more resistant to malaria than are individuals who are homozygous for the allele for normalhemoglobin (HbA). Their red blood cells are prone to sickling when there is a deficiency of oxygen.  Which of the following conclusions can be drawn from the information provided onsickle cell anemia?a. The sickle cell gene eventually will disappear because of its interaction with malaria.b. Malaria causes heterozygous individuals to be less fertile than homozygous individuals.c. In Africa, sickle cell anemia will disappear because it is lethal…

Sickle cell anemia is a disease that is caused by a mutation in the gene that produces hemoglobin.  Hemoglobin carries oxygen in red blood cells.  The HbA allele produces normal hemoglobin and the HbS allele produces hemoglobin that sticks together and causes red blood cells to sickle.  Heterozygous individuals (HbAHbS) produce both normal and "sickle" hemoglobin so the HbA and HbS alleles are codominant.  Heterozygotes do not develop sickle cell anemia and are described as having the sickle cell trait.  Individuals that are homozygous for the sickle allele (HbSHbS) only produce "sickle" hemoglobin and develop sickle cell disease. A man with the sickle cell trait married a woman with the sickle cell trait. Determine the probability that they will have children with the sickle cell trait or sickle cell disease.Record your answer as a value between 0 and 1 rounded to two decimal places.  Answer

A man with hemophilia has a daughter of normal phenotype. She marries a man who is normal for the trait. The probability of their son to be a hemophiliac is 1/4. Its true or false? Explain.

A couple are both phenotypically normal but their son suffers from hemophilla, a sex linked recessive disorder. What fraction of their children are likely to suffer from hemophilia. what fraction are likely to be carriers.

Which of the following conclusions can be drawn from all the information provided on sickle cell anemia? The malaria-causing microorganism Plasmodium falciparum is injected by mosquitoes into the bloodstream of humans. Historically, the frequency of the Hb allele in Africa relates directly to the presence of malaria-causing organisms. In western Africa, the frequency of the Hb allele in the gene pool is 0.15. In central Africa, the frequency is 0.10, and in southern Africa the frequency is 0.05. The sickle cell gene will eventually disappear because of its interaction with malaria. Malaria causes heterozygous individuals to be less fertile than homozygous individuals. In Africa, sickle cell anemia will disappear since it is lethal in the homozygous condition. In Africa, carriers for sickle cell anemia have an advantage over homozygous individuals. *