5. The following image is of ASO analysis performed at 90°C on a family with Ty Sachs (M and F are the parents, C1, C2 and C3 are the children), and 2 unrelated controls. These parents had a normal child and then had a child with Ty Sachs and they want to know if their third child will have it. The top ASO dot represents the Ty Sachs allele and the bottom represents the normal allele. TZ N M F C1 Control 1 Control 2

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Topic Video
Question
100%
5. The following image is of ASO
analysis performed at 90°C on a
family with Ty Sachs (M and F are the
parents, C1, C2 and C3 are the
children), and 2 unrelated controls.
These parents had a normal child and
then had a child with Ty Sachs and
they want to know if their third child
will have it. The top ASO dot
represents the Ty Sachs allele and
the bottom represents the normal
allele.
b. What is the status of the 3 children?
c. What are the controls?
TZ
N
a. What is the status of the parents? (Have disease, are carriers, are normal?)
d. The following panel is of a similar analysis
done, excpet the technician found that the
machine had been set to the wrong
temperature for analysis. Is the temperature
the machine set to higher or lower? Explain
why.
6. A murder victim is found in an advanced state of
decomposition and cannot be identified. Police
suspect that the victim is one of 5 individuals
reported missing by their parents. DNA typing
(RFLP) is carried out against those 5 sets of
parents.
According to loci 1 only, which couple could be the
parents of the dead individual found?
Who are the parents of the individual found
(combine both data)?
According to loci 2 only, which couple could be the
parents of the dead individual found?
M
ΤΖ
F
N
C1
C1
A B C D E
d d d d d d 59 59 x
Control 1
-
Control 1
Control 2
Control 2
A B C D E
6 9 6 2 d 98989 X
Transcribed Image Text:5. The following image is of ASO analysis performed at 90°C on a family with Ty Sachs (M and F are the parents, C1, C2 and C3 are the children), and 2 unrelated controls. These parents had a normal child and then had a child with Ty Sachs and they want to know if their third child will have it. The top ASO dot represents the Ty Sachs allele and the bottom represents the normal allele. b. What is the status of the 3 children? c. What are the controls? TZ N a. What is the status of the parents? (Have disease, are carriers, are normal?) d. The following panel is of a similar analysis done, excpet the technician found that the machine had been set to the wrong temperature for analysis. Is the temperature the machine set to higher or lower? Explain why. 6. A murder victim is found in an advanced state of decomposition and cannot be identified. Police suspect that the victim is one of 5 individuals reported missing by their parents. DNA typing (RFLP) is carried out against those 5 sets of parents. According to loci 1 only, which couple could be the parents of the dead individual found? Who are the parents of the individual found (combine both data)? According to loci 2 only, which couple could be the parents of the dead individual found? M ΤΖ F N C1 C1 A B C D E d d d d d d 59 59 x Control 1 - Control 1 Control 2 Control 2 A B C D E 6 9 6 2 d 98989 X
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps

Blurred answer
Knowledge Booster
Patterns of inheritance
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education