I 4 2 3 1 II #a 9 10 8 5 7 6 3 II 2 2 10 3 6 4 5 IV 1 3 6 7 8 2 5 9 8. If individuals IV-3 and IV-4 marry, what is the probability that their first child will have the disease? С. 1/64 Е. 1/16 А. 1/32 D. 1/12 B. 1/48 110! 9. Statistically, this trait has a probability of 0.0001 in the population in which these families live. If IV5 is married with a man who is also in this community. What is the probability if your first child has this trait? E. 0.246% B. 0.0413% C. 0.165% D. 0.123% A. 0.0825% 10. If the disease is inherited as an autosomal dominant trait with 50% penetrance, then what would be the possibility that the first child from the marriage of IV3 and IV4 shows this disease? A 1.0 B. 0.0417 E. None of the C. 0.0313 D. 0.1342 answers. CO --IN о

I 4 2 3 1 II #a 9 10 8 5 7 6 3 II 2 2 10 3 6 4 5 IV 1 3 6 7 8 2 5 9 8. If individuals IV-3 and IV-4 marry, what is the probability that their first child will have the disease? С. 1/64 Е. 1/16 А. 1/32 D. 1/12 B. 1/48 110! 9. Statistically, this trait has a probability of 0.0001 in the population in which these families live. If IV5 is married with a man who is also in this community. What is the probability if your first child has this trait? E. 0.246% B. 0.0413% C. 0.165% D. 0.123% A. 0.0825% 10. If the disease is inherited as an autosomal dominant trait with 50% penetrance, then what would be the possibility that the first child from the marriage of IV3 and IV4 shows this disease? A 1.0 B. 0.0417 E. None of the C. 0.0313 D. 0.1342 answers. CO --IN о

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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11. Using the following chart, what is the map distance between A and T? Gamete Genotype Gamete Type C C C C C C C C a. b. A a A a A a A a Total 30.4 CM 5.8 CM c. 24.6 cM d. 0.9 cM T t t T T t t T Progeny 4 5 118 119 356 349 24 25 1000
1
4. In this pedigree of another family with hemophilia A. If the woman Il-2 has a son, what is the chance that he is affected? II B. If the woman Il-2 has a daughter, what is the chance 1 2 3 4 III that she is affected? -1 C. If the woman Il-2 has 2 sons, what is the chance that neither will be affected? D. What are the chances that the child of II-4 and Il-5 will be affected?
Below is a pedigree for a family into which Individual III-4 has married. He and his spouse, Individual III-3, are visiting a genetic counselor because they are expecting a baby (Individual IV-1). They want to know the chance that the baby will get the autosomal recessive genetic disease seen in Individual II-2. Overall, in the population, the disease is known to affect 1 in 625 individuals in the population to which this family belongs [assume this frequency is the result of random mating so represents f(aa)] I. II. E III. IV. 1 1 2 2 3 1 3 1 4 2 4 5
Explain how you came up with this ratio?
3. For the following crosses, describe the genotype and phenotype frequencies of the offspring. I recommend using Punnett squares for each. Offspring phenotypes and frequencies А - 50% О -50% Parental Offspring genotypes and frequencies Parental genotypes phenotypes LAj x i Ai – 50% ii – 50% A and O Bị x Ai BIB x Ai AA x IBIB Bị x Bi AB x i
1.0 0.9 0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 0 1.0 0.9 g² (aa) p2 (AA) 0.8 Frequency of heterozygotes 0.7 is maximum 0.6 when p = q = 1/2 2pg (Aa) 0.5 0.4 0.3 0.2 0.1 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0 p = 1-9 What would be the frequency of heterozygotes if the frequency of q = 0.3? %D 0.4 0.5 0.6 0.7 Genotype frequency