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Part 1 What is the probability that each indicated individual is a carrier of the disease allele? For people with no family history, assume that the probability of carrier status is f(Aa) I. 11. III. IV. Incorrect 1 1 O 0.0096 O 0.0192 Oo Ⓒ 0.25 O 0.125 2 2 A1 1 2 1/2 x 2/3 0.016 0.0768 0 1 (100%) 1/4 1/2 9... Part 2 What is the chance that Individual IV-I will get the disease? Incorrect Individual III-3 has a 100% chance of being a carrier. Individual III-4 has a chance of 0.0768, as calculated from the frequency in the population. Use this information to calculate the chance that the two carriers could have an affected offspring.

Part 1 What is the probability that each indicated individual is a carrier of the disease allele? For people with no family history, assume that the probability of carrier status is f(Aa) I. 11. III. IV. Incorrect 1 1 O 0.0096 O 0.0192 Oo Ⓒ 0.25 O 0.125 2 2 A1 1 2 1/2 x 2/3 0.016 0.0768 0 1 (100%) 1/4 1/2 9... Part 2 What is the chance that Individual IV-I will get the disease? Incorrect Individual III-3 has a 100% chance of being a carrier. Individual III-4 has a chance of 0.0768, as calculated from the frequency in the population. Use this information to calculate the chance that the two carriers could have an affected offspring.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Below is a pedigree for a family into which Individual III-4 has married. He and his spouse, Individual III-3, are visiting a genetic counselor because they are expecting a baby (Individual IV-1). They want to know the chance that the baby will get the autosomal recessive genetic disease seen in Individual II-2. Overall, in the population, the disease is known to affect 1 in 625 individuals in the population to which this family belongs [assume this frequency is the result of random mating so represents f(aa)] I. II. E III. IV. 1 1 2 2 3 1 3 1 4 2 4 5
Transcribed Image Text:Below is a pedigree for a family into which Individual III-4 has married. He and his spouse, Individual III-3, are visiting a genetic counselor because they are expecting a baby (Individual IV-1). They want to know the chance that the baby will get the autosomal recessive genetic disease seen in Individual II-2. Overall, in the population, the disease is known to affect 1 in 625 individuals in the population to which this family belongs [assume this frequency is the result of random mating so represents f(aa)] I. II. E III. IV. 1 1 2 2 3 1 3 1 4 2 4 5
Part 1 What is the probability that each indicated individual is a carrier of the disease allele? For people with no family history, assume that the probability of carrier status is f(Aa) I. II. III. IV. 2/3 Incorrect O 0.0096 O 0.0192 O 0 O 0.25 1 O 0.125 1 2 2 3 1 Part 2 What is the chance that Individual IV-I will get the disease? 2 5 1/2 x 0.016 0.0768 0 1 (100%) 1/4 1/2 Incorrect Individual III-3 has a 100% chance of being a carrier. Individual III-4 has a chance of 0.0768, as calculated from the frequency in the population. Use this information to calculate the chance that the two carriers could have an affected offspring. X X X
Transcribed Image Text:Part 1 What is the probability that each indicated individual is a carrier of the disease allele? For people with no family history, assume that the probability of carrier status is f(Aa) I. II. III. IV. 2/3 Incorrect O 0.0096 O 0.0192 O 0 O 0.25 1 O 0.125 1 2 2 3 1 Part 2 What is the chance that Individual IV-I will get the disease? 2 5 1/2 x 0.016 0.0768 0 1 (100%) 1/4 1/2 Incorrect Individual III-3 has a 100% chance of being a carrier. Individual III-4 has a chance of 0.0768, as calculated from the frequency in the population. Use this information to calculate the chance that the two carriers could have an affected offspring. X X X
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