20. The pedigree to the right shows the results of SSR genotyping of a family. The grandmother is affected with a fully penetrant, adult onset autosomal disease. The exact genetic lesion is not known, but it has been 22 mapped to be 4 centimorgans from the genotyping SSR. What is the likelihood that Child B will suffer from the disease? 13 12 32 a. 2% b. 4% C. 48% d. 50% 12 32 A B

20. The pedigree to the right shows the results of SSR genotyping of a family. The grandmother is affected with a fully penetrant, adult onset autosomal disease. The exact genetic lesion is not known, but it has been 22 mapped to be 4 centimorgans from the genotyping SSR. What is the likelihood that Child B will suffer from the disease? 13 12 32 a. 2% b. 4% C. 48% d. 50% 12 32 A B

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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1. Use the diagram of the pedigree above, which shows inheritance of an x-linked recessive trait through a family. Select ALL of the individuals in the pedigree who must be carriers for the trait. E G B C H A
4. In this pedigree of another family with hemophilia A. If the woman Il-2 has a son, what is the chance that he is affected? II B. If the woman Il-2 has a daughter, what is the chance 1 2 3 4 III that she is affected? -1 C. If the woman Il-2 has 2 sons, what is the chance that neither will be affected? D. What are the chances that the child of II-4 and Il-5 will be affected?
1. Given: CcWwGg X CcWwGg Full, Round, Yellow Full, Round, Yellow Recessive Traits: Constricted, Wrinkled, Green Problem: Determine the F1 Phenotype
reference text Ph.D Fernando, Harvard Professor of Genetic Epidemiology, knows a thing or two about Twins. He must know as he is head of the Twin Research Department where he works with about 3,500 pairs of identical twins, researching the influence of a person's genes on everything from the probability of being obese, whether or not they have religious beliefs, and, how, do they fall into sentimental issues. Anyone who is a twin, or who has ever met a pair of identical twins, can attest to how remarkably similar they are to each other, even in the rare cases of adopted twins raised in separate homes.A recent article begins with an introduction to two middle-aged twin sisters called Susan and Polly, one of the pairs of twins in the study group of the Department of Research of Harvard. Although they were treated almost as a single person growing up, with cuts from identical hair and clothes, the twins began to diverge in their teens as they they gained the freedom to make their own…
II. Given the following pedigree below, use Punnett squares for each of the following possibilities: a) Autosomal recessive and b) Autosomal dominant in order to determine what is the mode of transmission of this trait. Disease allele = a or A, depending on mode of transmission of the disease respectively. Your Punnett squares should reflect what you see in generation II. Circle the mode of transmission. Note: Observe the whole pedigree. I Circle the mode of transmission 1 III 6 genotype (circle one): AA Created by Dr. Susan A. Holechek for BIO 340 (2023) 2 1 2 3 4 a) Autosomal recessive 11 x 12 9 XªXa 2 3 5 6 Ở хаха *4 7 b) Autosomal dominant 11x12 8 Aa *Unaffected/No carrier-Normal AaAa
1. Is there a possibility that Joe's father has a genotype HH ? 2. The question does not mention that Joe's mother is hh.
Please write or type out the genotypes of each individual on the pedigree in a clear way
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3. For the following crosses, describe the genotype and phenotype frequencies of the offspring. I recommend using Punnett squares for each. Offspring phenotypes and frequencies А - 50% О -50% Parental Offspring genotypes and frequencies Parental genotypes phenotypes LAj x i Ai – 50% ii – 50% A and O Bị x Ai BIB x Ai AA x IBIB Bị x Bi AB x i
20. Based on the pedigree below, what do you know about individual II-3 and II-4? Examine the pedigree below. 1 11 111 IV DO 1 Figure 12-3 They have the disease They are both homozygous recesive *REQU They are both carriers They are both homozygous dominant
I believe it to be 50% but I'm not sure.