**Problem 3: Synthetic Traps in Reactions**One of the reactions shown below (a-b) is not valid and is considered a synthetic trap. Identify which proposed reaction is not valid and draw the correct expected product.**Reaction (a):**1. LDA (Lithium diisopropylamide)2. Bromine (Br)- Reactants: A ketone with a 3-carbon chain and a methyl group attached to the alpha position.- Proposed Product: A ketone with the same 3-carbon chain, but the methyl group has been moved to a new position.**Reaction (b):**- Reactants: A ketone with a 3-carbon chain.- Reagents: HCl (Hydrochloric acid)- Final Product: A compound with an alcohol (OH) and a chlorine (Cl) on an ethyl chain.**Explanation:**In reaction (a), LDA is a strong base used for deprotonating the alpha position of ketones to form enolates. The reaction suggests an alpha-halogenation with bromine.Reaction (b) involves hydrochloric acid, implying a nucleophilic substitution or an addition reaction to a ketone, resulting in a compound with an alcohol and chlorine group.**Task:**Identify the inappropriate reaction step or product and propose the correct expected product based on fundamental organic chemistry principles.

3. One of the reactions shown below (a-b) is not valid and is considered a synthetic trap. Identify which proposed reaction is not valid and draw the correct expected product. (a) (b) 1. LDA 2. Br e مرا مدم HCI HO

3. One of the reactions shown below (a-b) is not valid and is considered a synthetic trap. Identify which proposed reaction is not valid and draw the correct expected product. (a) (b) 1. LDA 2. Br e مرا مدم HCI HO

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Concept explainers

Reactions of Ethers

Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.

Epoxides

Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.

Williamson Ether Synthesis

An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.

Question

**Problem 3: Synthetic Traps in Reactions**

One of the reactions shown below (a-b) is not valid and is considered a synthetic trap. Identify which proposed reaction is not valid and draw the correct expected product.

**Reaction (a):**

1. LDA (Lithium diisopropylamide)
2. Bromine (Br)

- Reactants: A ketone with a 3-carbon chain and a methyl group attached to the alpha position.
- Proposed Product: A ketone with the same 3-carbon chain, but the methyl group has been moved to a new position.

**Reaction (b):**

- Reactants: A ketone with a 3-carbon chain.
- Reagents: HCl (Hydrochloric acid)
- Final Product: A compound with an alcohol (OH) and a chlorine (Cl) on an ethyl chain.

**Explanation:**

In reaction (a), LDA is a strong base used for deprotonating the alpha position of ketones to form enolates. The reaction suggests an alpha-halogenation with bromine.

Reaction (b) involves hydrochloric acid, implying a nucleophilic substitution or an addition reaction to a ketone, resulting in a compound with an alcohol and chlorine group.

**Task:**

Identify the inappropriate reaction step or product and propose the correct expected product based on fundamental organic chemistry principles.

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