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- Fluvastatin, a cholesterol-lowering drug, can be prepared by thefollowing three-step reaction sequence. Identify intermediates A and Band the final product, fluvastatin.Identify A, B, and C, intermediates in the synthesis of the five-membered ring called an α- methylene-γ-butyrolactone. This heterocyclic ring system is present in some antitumor agents.Which compound is the major product of the reaction below? HO OH 11419 HO, он TSOH (cat) (A) (В) (D) (C) O Compound B Compound D Compound C Compound A
- Which compound is the major product of the reaction below? H2 Pd'charcoal (A) (B) (C) (D) Compound D Compound A Compound B O Compound C ncti 19 12 (4)Show the products from reaction of p-bromoaniline with the following reagents: (a) CH3I (excess) (b) HCl (c) HNO2, H2SO4 (d) CH3COCl (e) CH3MgBr (f) CH3CH2Cl, AlCl3 (g) Product of (c) with CuCl, HCl (h) Product of (d) with CH3CH2Cl, AlCl3Identify A, B, and C, intermediates in the synthesis of the ve-membered ring called an α-methylene-γ-butyrolactone. This heterocyclic ring system is present in some antitumor agents.
- 22Nicotinic acid, more commonly named niacin, is one of the B vitamins. Show how nico- tinic acid can be converted to (a) ethyl nicotinate and then to (b) nicotinamide. COH COET CNH, Nicotinic acid Ethyl nicotinate Nicotinamide (Niacin)Which is the major product of the reaction below? (1) Na EtO /EIOH (2) dil H*, H-O (A) (B) H2COO OCH3 (C) OCH3 (D) OCH3 Compound A Compound D Compound C Compound B
