29. Huntington disease results from expansion of a CAG triplet within the first exon of the huntingtin (HD) gene. This genetic defect most likely results in which of the following? OA) Abnormal polyglutamine tract within the huntingtin protein B) Abnormal splicing of huntingtin mRNA C) Decreased transcription of huntingtin mRNA D) Premature translation termination E) Shifted translation frame

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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29. Huntington disease results from expansion of a CAG triplet within the first exon of the huntingtin (HD) gene. This genetic defect most likely results in which of the
following?
DA) Abnormal polyglutamine tract within the huntingtin protein
B) Abnormal splicing of huntingtin mRNA
C) Decreased transcription of huntingtin mRNA
D) Premature translation termination
E) Shifted translation frame
ined
Transcribed Image Text:29. Huntington disease results from expansion of a CAG triplet within the first exon of the huntingtin (HD) gene. This genetic defect most likely results in which of the following? DA) Abnormal polyglutamine tract within the huntingtin protein B) Abnormal splicing of huntingtin mRNA C) Decreased transcription of huntingtin mRNA D) Premature translation termination E) Shifted translation frame ined
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