2.5 Chr 1 Chr 6 1.5 Chr 13 Chr 14 Chr 10 1 Chr 12 Chr 16 Chr 18 0.5 11 12 13 14 15 16 17 18 Length of embryonic development (days) [E. Torres, B. R. Williams, and A. Amon. 2008. Genetics 179:737- 746, Fig. 2B.] Size of mouse chromosomes (108 bp)
Using breeding techniques, Andrei Dyban and V. S. Baranov (Cytogenetics of Mammalian Embryonic Development. Oxford: Oxford University Press, Clarendon Press; New York: Oxford University Press, 1987) created mice that were trisomic for each of the different mouse chromosomes. They found that only mice with trisomy 19 developed. Mice that were trisomic for all other chromosomes died in the course of development. For some of these trisomics, the researchers plotted the length of development (number of days after conception before the embryo died) as a function of the size of the mouse chromosome that was present in three copies (see the adjoining graph). Summarize their findings and provide a possible explanation for the results.
![2.5
Chr 1
Chr 6
1.5
Chr 13 Chr 14
Chr 10
1
Chr 12
Chr 16 Chr 18
0.5
11 12 13 14 15 16 17 18
Length of embryonic
development (days)
[E. Torres, B. R. Williams, and A. Amon. 2008. Genetics 179:737-
746, Fig. 2B.]
Size of mouse
chromosomes (108 bp)](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F53757b5e-ea5c-448a-ad88-92493887cbb9%2F6cdd9530-b6ee-4169-aa6b-a1a4aa79e3db%2Fh0ju9po.jpeg&w=3840&q=75)
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