Which of the below explains why trisomy is better tolerated in humans than monosomy? (Select all correct options). a. Loss of heterozygosity in monosomy b. Increased gene expression in trisomic cells is beneficial c. Reduced gene expression in monosomy d.The extra chromosome in trisomic cells is degraded

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
icon
Concept explainers
Question

Which of the below explains why trisomy is better tolerated in humans than monosomy? (Select all correct options).

a. Loss of heterozygosity in monosomy
b. Increased gene expression in trisomic cells is beneficial
c. Reduced gene expression in monosomy
d.The extra chromosome in trisomic cells is degraded

 

 

Which two are both necessary to hold a tetrad together until Anaphase I?

a) nondisjunction

b) cross over

c) centromere cohesion

d) synaptonemal complex

e) separese activity

Expert Solution
Step 1

1.

<!--<SUB-PART>-->

(a)

<!--<SUMMARY-INTRODUCTION>-->

To Determine: If the given statement is true or false.

Introduction: Aneuploidy, a type of chromosomal abnormality, is highly prevalent in humans. When you have an extra copy of a chromosome, trisomy diseases develop. When one copy of a chromosome is absent, you have monosomy. Because a full missing autosome is almost always fatal, monosomies, which occur when the zygote obtains only one copy of a chromosome, are generally much less common than trisomies. Trisomy is more tolerated than monosomy for this reason.

 

<!--<ANSWER>-->

 

The given statement is true.

<!--</ANSWER>-->

 

<!--<EXPLANATION>-->

The loss of one parent's contribution to the cell is called the loss of heterozygosity. In this instance, it is brought on by monosomy or chromosome loss. In most monosomy situations, which are fatal, the foetus is not viable.

 

steps

Step by step

Solved in 4 steps

Blurred answer
Knowledge Booster
Genetic recombination
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education