Scenario 2: Down's syndrome can be caused by either a trisomy of chromosome 21 (2n=47 (+21)) or a translocation of chromosome 21, often onto chromosome 14 (2n=46 (t14/21). Question 5: Are there any nondisjunction events involving chromosome 21 that would not lead to at least one possible gamete forming a trisomy of chromosome 21 when fertilized with a karyotypically normal gamete? Circle one, then explain. YES No Question 5: If a parent is a carrier for familial Down's syndrome (Has a 14/21 translocation) answer the probabilities for each of the following offspring: A. Genotypically "normal"
Scenario 2: Down's syndrome can be caused by either a trisomy of chromosome 21 (2n=47 (+21)) or a translocation of chromosome 21, often onto chromosome 14 (2n=46 (t14/21). Question 5: Are there any nondisjunction events involving chromosome 21 that would not lead to at least one possible gamete forming a trisomy of chromosome 21 when fertilized with a karyotypically normal gamete? Circle one, then explain. YES No Question 5: If a parent is a carrier for familial Down's syndrome (Has a 14/21 translocation) answer the probabilities for each of the following offspring: A. Genotypically "normal"
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Scenario 2: Down's syndrome can be caused by either a trisomy of chromosome 21
(2n=47 (+21)) or a translocation of chromosome 21, often onto chromosome 14 (2n=46
(t14/21).
Question 5: Are there any nondisjunction events involving chromosome 21 that would
not lead to at least one possible gamete forming a trisomy of chromosome 21 when
fertilized with a karyotypically normal gamete? Circle one, then explain.
YES
Question 5: If a parent is a carrier for familial Down's syndrome (Has a 14/21
translocation) answer the probabilities for each of the following offspring:
A. Genotypically "normal"
B. Carrier, but phenotypically without symptom
C. Down's syndrome phenotype
No
D. Lethal before birth due to haploinsufficiency
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